Sox5 contributes to prostate cancer metastasis and is a master regulator of TGF-β-induced epithelial mesenchymal transition through controlling Twist1 expression

被引：0
|
作者：
Jieping Hu
Jing Tian
Shimiao Zhu
Libin Sun
Jianpeng Yu
Hao Tian
Qian Dong
Qiang Luo
Ning Jiang
Yuanjie Niu
Zhiqun Shang
机构：
[1] Tianjin Institute of Urology,Department of Urology
[2] the Second Hospital of Tianjin Medical University,Department of Urology
[3] the First Affiliated Hospital of Nanchang University,undefined
[4] First Affiliated Hospital,undefined
[5] Shanxi Medical University,undefined
来源：
British Journal of Cancer | 2018年 / 118卷
关键词：
mCRPC; EMT; Sox5; TGF-; Twist1; survival;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：88 / 97
页数：9
相关论文
共 50 条
  • [31] Twist1 and AP-1 cooperatively upregulate integrin α5 expression to induce invasion and the epithelial-mesenchymal transition
    Nam, Eun-Hee
    Lee, Yunhee
    Moon, Byul
    Lee, Jung Weon
    Kim, Semi
    CARCINOGENESIS, 2015, 36 (03) : 327 - 337
  • [32] PAQR3 enhances Twist1 degradation to suppress epithelial-mesenchymal transition and metastasis of gastric cancer cells
    Guo, Weiwei
    You, Xue
    Xu, Daqian
    Zhang, Yuxue
    Wang, Zheng
    Man, Kaiyang
    Wang, Zhenzhen
    Chen, Yan
    CARCINOGENESIS, 2016, 37 (04) : 397 - 407
  • [33] The role of fad104, a positive regulator for adipogenesis, in TGF-β1-induced epithelial to mesenchymal transition
    Goto, M.
    Nishizuka, M.
    Osada, S.
    Imagawa, M.
    MOLECULAR BIOLOGY OF THE CELL, 2016, 27
  • [34] TGF-β-induced transgelin promotes bladder cancer metastasis by regulating epithelial-mesenchymal transition and invadopodia formation
    Chen, Zhicong
    He, Shiming
    Zhan, Yonghao
    He, Anbang
    Fang, Dong
    Gong, Yanqing
    Li, Xuesong
    Zhou, Liqun
    EBIOMEDICINE, 2019, 47 : 208 - 220
  • [35] miR-190 suppresses breast cancer metastasis by regulation of TGF-β-induced epithelial-mesenchymal transition
    Yu, Yue
    Luo, Wei
    Yang, Zheng-Jun
    Chi, Jiang-Rui
    Li, Yun-Rui
    Ding, Yu
    Ge, Jie
    Wang, Xin
    Cao, Xu-Chen
    MOLECULAR CANCER, 2018, 17
  • [36] RhoC is essential in TGF-β1 induced epithelial-mesenchymal transition in cervical cancer cells
    He, Xiaoqi
    Qian, Ying
    Cai, Huilan
    Yang, Shouhua
    Cai, Jing
    Wang, Zehua
    ONCOLOGY LETTERS, 2015, 10 (02) : 985 - 989
  • [37] CDK5 is essential for TGF-β1-induced epithelial-mesenchymal transition and breast cancer progression
    Liang, Qian
    Li, Lili
    Zhang, Jianchao
    Lei, Yang
    Wang, Liping
    Liu, Dong-Xu
    Feng, Jingxin
    Hou, Pingfu
    Yao, Ruosi
    Zhang, Yu
    Huang, Baiqu
    Lu, Jun
    SCIENTIFIC REPORTS, 2013, 3
  • [38] CDK5 is essential for TGF-β1-induced epithelial-mesenchymal transition and breast cancer progression
    Qian Liang
    Lili Li
    Jianchao Zhang
    Yang Lei
    Liping Wang
    Dong-Xu Liu
    Jingxin Feng
    Pingfu Hou
    Ruosi Yao
    Yu Zhang
    Baiqu Huang
    Jun Lu
    Scientific Reports, 3
  • [39] The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial–mesenchymal transition and invasive properties of prostate cancer
    T Ezponda
    R Popovic
    M Y Shah
    E Martinez-Garcia
    Y Zheng
    D-J Min
    C Will
    A Neri
    N L Kelleher
    J Yu
    J D Licht
    Oncogene, 2013, 32 : 2882 - 2890
  • [40] MicroRNA-124 regulates TGF-α-induced epithelial-mesenchymal transition in human prostate cancer cells
    Qin, Wei
    Pan, Yujia
    Zheng, Xiulan
    Li, Dong
    Bu, Jingyi
    Xu, Chunyan
    Tang, Jiebing
    Cui, Rongjun
    Lin, Ping
    Yu, Xiaoguang
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2014, 45 (03) : 1225 - 1231
12345