Alzheimer disease: BACE1 inhibitor reduces β-amyloid production in humans

被引:0
|
作者
Crunkhorn S.
机构
关键词
D O I
10.1038/nrd.2016.271
中图分类号
学科分类号
摘要
[No abstract available]
引用
收藏
页码:18 / 18
相关论文
共 50 条
  • [21] Cerebrospinal Fluid BACE1 Activity and Brain Amyloid Load in Alzheimer's Disease
    Grimmer, Timo
    Alexopoulos, Panagiotis
    Tsolakidou, Amalia
    Guo, Liang-Hao
    Henriksen, Gjermund
    Yousefi, Behrooz H.
    Foerstl, Hans
    Sorg, Christian
    Kurz, Alexander
    Drzezga, Alexander
    Perneczky, Robert
    [J]. SCIENTIFIC WORLD JOURNAL, 2012,
  • [22] Associations of CSF BACE1 with amyloid pathology, neurodegeneration, and cognition in Alzheimer's disease
    Gao, Feng
    Zhang, Mengguo
    Wang, Qiong
    Ni, Ming
    Liu, Chang
    Deng, Kexue
    Xie, Qiang
    Wang, Shicung
    Shi, Jiong
    Shen, Yong
    [J]. ACTA NEUROPATHOLOGICA, 2024, 147 (01)
  • [23] Astragaloside IV, a Natural PPARγ Agonist, Reduces Aβ Production in Alzheimer's Disease Through Inhibition of BACE1
    Wang, Xu
    Wang, Yue
    Hu, Jiang-Ping
    Yu, Song
    Li, Bao-Kun
    Cui, Yong
    Ren, Lu
    Zhang, Li-De
    [J]. MOLECULAR NEUROBIOLOGY, 2017, 54 (04) : 2939 - 2949
  • [24] Astragaloside IV, a Natural PPARγ Agonist, Reduces Aβ Production in Alzheimer’s Disease Through Inhibition of BACE1
    Xu Wang
    Yue Wang
    Jiang-Ping Hu
    Song Yu
    Bao-Kun Li
    Yong Cui
    Lu Ren
    Li-De Zhang
    [J]. Molecular Neurobiology, 2017, 54 : 2939 - 2949
  • [25] Advancements in BACE1 and non-peptide BACE1 inhibitors for Alzheimer's disease
    Shah, Nishita P.
    Solanki, Vivek S.
    Gurjar, Archana S.
    [J]. INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2018, 57 (06): : 830 - 842
  • [26] Indapamide suppresses amyloid-β production in cellular models of Alzheimer's disease through regulating BACE1 activity
    Lu, Mei
    Ma, Lin
    Wang, Xinbang
    Jiang, Wenjing
    Shan, Peiyan
    [J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2017, 10 (04): : 5922 - 5930
  • [27] Stepping closer to treating Alzheimer’s disease patients with BACE1 inhibitor drugs
    Riqiang Yan
    [J]. Translational Neurodegeneration, 5
  • [28] In Silico Design of BACE1 Inhibitor for Alzheimer′s Disease by Traditional Chinese Medicine
    Huang, Hung-Jin
    Lee, Cheng-Chun
    Chen, Calvin Yu-Chian
    [J]. BIOMED RESEARCH INTERNATIONAL, 2014, 2014
  • [29] Influence of a tripartite BACE1 inhibitor on retina in an Alzheimer's disease mouse model
    Loeffler, Jana
    Karich, Felix
    Knels, Claudia
    Valtink, Monika
    Knoelker, Hans-Joachim
    Funk, Richard
    Schroeder, Cornelia
    Knels, Lilla
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2014, 55 (13)
  • [30] The Alzheimer's disease β-secretase enzyme, BACE1
    Cole, Sarah L.
    Vassar, Robert
    [J]. MOLECULAR NEURODEGENERATION, 2007, 2 (1)