NMR assignment of Cdc42(T35A), an active Switch I mutant of Cdc42

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作者
Paul D. Adams
Robert E. Oswald
机构
[1] University of Arkansas-Fayetteville,Department of Chemistry and Biochemistry
[2] Cornell University College of Veterinary Medicine,Department of Molecular Medicine
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关键词
Cdc42(T35A); Ras GTPase; Signal transduction;
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摘要
Cdc42(T35A) is an active construct of Cdc42, a Ras GTPase involved in signal transduction, containing a single-point mutation in an important effector-binding region. We determined the backbone and side chain resonance assignments of 13C,15N-labelled Cdc42(T35A) from E. coli.
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页码:225 / 227
页数:2
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