Blood Serum Levels of Proinflammatory Cytokines (IL-1β, IL-6, TNFα, IL-8, IL-12p70, and IFNγ) in Patients with Uterine Myoma

被引：0
|
作者：
V. I. Konenkov
E. G. Koroleva
N. B. Orlov
V. F. Prokof’ev
A. V. Shevchenko
A. M. Novikov
T. I. Dergacheva
机构：
[1] Siberian Division of the Russian Academy of Sciences,Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics
来源：
Bulletin of Experimental Biology and Medicine | 2018年 / 165卷
关键词：
IL-1β; IL-6; TNFα; IL-8; uterine myoma;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We analyzed cytokine profile in blood serum of patients with uterine myoma and revealed significantly reduced level of IFNγ and a tendency towards a decrease in the levels of IL-1β and TNFα; the levels of IL-6, IL-8, and IL-12p70 did not differ from those in healthy women. The drop in the concentrations of factors responsible for inflammation and angiogenesis in tissues are unfavorable for proliferation and differentiation of the uterine tissues.
引用
收藏
页码：698 / 701
页数：3
相关论文
共 50 条
  • [11] Serum IL-1β, IL-6, IL-8, and TNF-α levels in early diagnosis and management of neonatal sepsis
    Kurt, A. Nese Citak
    Aygun, A. Denizmen
    Godekmerdan, Ahmet
    Kurt, Abdullah
    Dogan, Yasar
    Yilmaz, Erdal
    MEDIATORS OF INFLAMMATION, 2007, 2007
  • [12] Effects of febuxostat on serum cytokines IL-1, IL-4, IL-6, IL-8, TNF- and COX-2
    Hao, Guohua
    Duan, Wei
    Sun, Jianping
    Liu, Jingyao
    Peng, Bo
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 17 (01) : 812 - 816
  • [13] Proinflammatory cytokines IL-6, IL-1 β, TNF-α in infective endocarditis
    Kotova, Elizaveta O.
    Moiseeva, Alexandra Yu.
    Kobalava, Zhanna D.
    Lokhonina, Anastasiya V.
    Pisaryuk, Alexandra S.
    Gusarova, Tatyana A.
    Fatkhudinov, Timur Kh.
    Domonova, Elvira A.
    TERAPEVTICHESKII ARKHIV, 2024, 96 (04) : 342 - 348
  • [14] Inflammatory cytokines:: TNFα, IL-1β, IL-6 and IL-8 in pulmonary hypertension of sickle cell disease
    Vicari, Perla
    Noeuti, Maria Aparecida E.
    Morelli, Vania M.
    Cancado, Rodolfo D.
    Figueiredo, Maria Stella
    BLOOD, 2007, 110 (11) : 14B - 14B
  • [15] Altered expression of cytokines IL-1α, IL-6, IL-8 and TNF-α in bovine follicular persistence
    Stassi, A. F.
    Baravalle, M. E.
    Belotti, E. M.
    Rey, F.
    Gareis, N. C.
    Diaz, P. U.
    Rodriguez, F. M.
    Leiva, C. J.
    Ortega, H. H.
    Salvetti, N. R.
    THERIOGENOLOGY, 2017, 97 : 104 - 112
  • [16] Role of fibroblasts in the regulation of proinflammatory interleukin IL-1, IL-6 and IL-8 levels induced by keratinocyte-derived IL-1
    Boxman, ILA
    Ruwhof, C
    Boerman, OC
    Lowik, CWGM
    Ponec, M
    ARCHIVES OF DERMATOLOGICAL RESEARCH, 1996, 288 (07) : 391 - 398
  • [17] Expression of proinflammatory cytokines IL-1β, IL-6 and TNFα in the retained placenta of mares
    Jaworska, J.
    Janowski, T.
    REPRODUCTION IN DOMESTIC ANIMALS, 2018, 53 : 148 - 148
  • [18] Expression of proinflammatory cytokines IL-1β, IL-6 and TNFα in the retained placenta of mares
    Jaworska, J.
    Janowski, T.
    THERIOGENOLOGY, 2019, 126 : 1 - 7
  • [19] 结肠癌患者细胞因子IFN-γ、IL-12P40、IL-12P70、IL-6、IL-8和TNF-α的表达分析
    梁春芳
    数理医药学杂志, 2019, 32 (12) : 1784 - 1785
  • [20] IL-1β and TNF-α, but not IFN-α, IFN-γ, IL-6 or IL-8, are secretory mediators in human distal colon
    Bode, H
    Schmitz, H
    Fromm, M
    Scholz, P
    Riecken, EO
    Schulzke, JD
    CYTOKINE, 1998, 10 (06) : 457 - 465
12345