Blood Serum Levels of Proinflammatory Cytokines (IL-1β, IL-6, TNFα, IL-8, IL-12p70, and IFNγ) in Patients with Uterine Myoma

被引:0
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作者
V. I. Konenkov
E. G. Koroleva
N. B. Orlov
V. F. Prokof’ev
A. V. Shevchenko
A. M. Novikov
T. I. Dergacheva
机构
[1] Siberian Division of the Russian Academy of Sciences,Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics
关键词
IL-1β; IL-6; TNFα; IL-8; uterine myoma;
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摘要
We analyzed cytokine profile in blood serum of patients with uterine myoma and revealed significantly reduced level of IFNγ and a tendency towards a decrease in the levels of IL-1β and TNFα; the levels of IL-6, IL-8, and IL-12p70 did not differ from those in healthy women. The drop in the concentrations of factors responsible for inflammation and angiogenesis in tissues are unfavorable for proliferation and differentiation of the uterine tissues.
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页码:698 / 701
页数:3
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