Multiple sclerosis and amyloid deposits in the white matter of the brain

被引:0
|
作者
I. Nennesmo
Nenad Bogdanovic
Anna-Lena Petrén
Sten Fredrikson
机构
[1] Division of Pathology,
[2] Karolinska Institute,undefined
[3] Huddinge Hospital,undefined
[4] S-141 86 Huddinge,undefined
[5] Sweden Tel.: 46-8-746 10 00; Fax: 46-8-779 55 20; e-mail: inne@patd01.hs.sll.se,undefined
[6] Department of Clinical Neuroscience and Family Medicine,undefined
[7] Geriatric Section,undefined
[8] Karolinska Institute,undefined
[9] Huddinge Hospital,undefined
[10] Huddinge,undefined
[11] Sweden,undefined
[12] Division of Pathology,undefined
[13] Karolinska Institute,undefined
[14] Huddinge Hospital,undefined
[15] Huddinge,undefined
[16] Sweden,undefined
[17] Division of Neurology,undefined
[18] Karolinska Institute,undefined
[19] Huddinge Hospital,undefined
[20] Huddinge,undefined
[21] Sweden,undefined
来源
Acta Neuropathologica | 1997年 / 93卷
关键词
Key words Multiple sclerosis; Amyloid; White; matter; Immunoglobulins;
D O I
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中图分类号
学科分类号
摘要
We present the neuropathological findings in a female patient with clinically definite multiple sclerosis (MS), who at autopsy had multifocal amyloid deposits in the white matter of the brain without other signs of amyloidosis. The patient had relapsing/remitting MS between the ages of 26 and 45, and during her last 14 years she had a secondary chronic progressive form of MS. Previous reports of amyloid deposits in MS are reviewed and the possible relationship between amyloid deposits and the increased production of immunoglobulin free light chains in MS is discussed.
引用
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页码:205 / 209
页数:4
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