Matrix MetalloproteinasesNovel Targets for Directed Cancer Therapy

被引：0
|
作者：
Anita E. Yu
Robert E. Hewitt
Edward W. Connor
William G. Stetler-Stevenson
机构：
[1] National Cancer Institute,Laboratory of Pathology
[2] National Institutes of Health,Extracellular Matrix Pathology Section, Laboratory of Pathology
[3] DCS/NCI/NIH,undefined
来源：
Drugs & Aging | 1997年 / 11卷
关键词：
Adis International Limited; Collagenase; Tissue Inhibitor; Human Amniotic Membrane; Matrix Metalloproteinase Inhibitor;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Matrix metalloproteinases (MMPs), or matrixins, are a family of zinc endopeptidases that play a key role in both physiological and pathological tissue degradation. Normally, there is a careful balance between cell division, matrix synthesis and matrix degradation, which is under the control of cytokines, growth factors and cell matrix interactions. The MMPs are involved in remodelling during tissue morphogenesis and wound healing.
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收藏
页码：229 / 244
页数：15
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