Dinucleotide repeat polymorphism in the third intron of the NRAMP2/DMT1 gene

被引：0
|
作者：
F. Kishi
S. Fujishima
M. Tabuchi
机构：
[1] Center for Gene Research,
[2] Yamaguchi University,undefined
[3] 1-1-1 Minami-Kogushi,undefined
[4] Ube,undefined
[5] Yamaguchi 755-8505,undefined
[6] Japan Tel. +81-836-22-2183; Fax +81-836-22-2185 e-mail: fkishi-ygc@umin.ac.jp,undefined
[7] Department of Emergency and Critical Care Medicine,undefined
[8] School of Medicine,undefined
[9] Keio University,undefined
[10] Tokyo,undefined
[11] Japan,undefined
来源：
Journal of Human Genetics | 1999年 / 44卷
关键词：
Key wordsNRAMP2; DMT1; Dinucleotide repeat; Iron transport;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Nramp1 (natural resistance-associated macrophage protein 1), encoding a polytropic integral membrane protein, was isolated as a candidate of the mouse Lsh/Ity/Bcg locus, which regulates macrophage activation for antimicrobial activity against intracellular pathogens. The NRAMP2 gene was cloned from human genome as a homologue of NRAMP1. We found a polymorphic dinucleotide repeat in the third intron of the NRAMP2 gene. This polymorphism will be a useful genetic marker to study disease associated with susceptibility to infection with intracellular pathogens.
引用
收藏
页码：425 / 427
页数：2
相关论文
共 50 条
  • [41] TRANSCRIBED DINUCLEOTIDE REPEAT POLYMORPHISM IN THE IGF2 GENE
    RAINIER, S
    DOBRY, CJ
    FEINBERG, AP
    [J]. HUMAN MOLECULAR GENETICS, 1994, 3 (02) : 386 - 386
  • [42] Dinucleotide repeat polymorphism in intron II of human Toll-like receptor 2 gene and susceptibility to rheumatoid arthritis
    Lee, E. Y.
    Yim, J. -J.
    Lee, H. S.
    Lee, Y. J.
    Lee, E. B.
    Song, Y. W.
    [J]. INTERNATIONAL JOURNAL OF IMMUNOGENETICS, 2006, 33 (03) : 211 - 215
  • [43] DMT1 gene polymorphism and blood Pb and Fe levels in Turkish metallurgy workers
    Odabasi, Miyase
    Kayaalti, Zeliha
    Yilmaz, Hinc
    Kurt, Ismail
    Soylemezoglu, Tulin
    [J]. TOXICOLOGY LETTERS, 2012, 211 : S144 - S145
  • [44] DINUCLEOTIDE REPEAT POLYMORPHISM IN THE HUMAN ANGIOTENSINOGEN GENE
    KOTELEVTSEV, YV
    CLAUSER, E
    CORVOL, P
    SOUBRIER, F
    [J]. NUCLEIC ACIDS RESEARCH, 1991, 19 (24) : 6978 - 6978
  • [45] DINUCLEOTIDE REPEAT POLYMORPHISM IN THE PROTEOLIPOPROTEIN (PLP) GENE
    MIMAULT, C
    CAILLOUX, F
    GIRAUD, G
    DASTUGUE, B
    BOESPFLUGTANGUY, O
    [J]. HUMAN GENETICS, 1995, 96 (02) : 236 - 236
  • [46] DINUCLEOTIDE REPEAT POLYMORPHISM AT THE HUMAN TYROSINASE GENE
    MORRIS, SW
    MUIR, W
    STCLAIR, D
    [J]. NUCLEIC ACIDS RESEARCH, 1991, 19 (24) : 6968 - 6968
  • [47] DINUCLEOTIDE REPEAT POLYMORPHISM IN THE HUMAN CERULOPLASMIN GENE
    DAIMON, M
    MORITA, Y
    YAMATANI, K
    IGARASHI, M
    FUKASE, N
    KAWANAMI, T
    KATO, T
    TOMINAGA, M
    SASAKI, H
    [J]. HUMAN GENETICS, 1995, 96 (06) : 736 - 736
  • [48] DINUCLEOTIDE REPEAT POLYMORPHISM AT THE HUMAN PREPROGLUCAGON GENE
    POLYMEROPOULOS, MH
    RATH, DS
    XIAO, H
    MERRIL, CR
    [J]. NUCLEIC ACIDS RESEARCH, 1991, 19 (03) : 688 - 688
  • [49] DINUCLEOTIDE INSERTION DELETION POLYMORPHISM IN INTRON-50 OF THE COL2A1 GENE
    TILLER, GE
    COHN, DH
    [J]. NUCLEIC ACIDS RESEARCH, 1991, 19 (15) : 4305 - 4305
  • [50] EGFR intron 1 dinucleotide repeat polymorphism is associated with the occurrence of skin rash with gefitinib treatment
    Huang, Chin-Lun
    Yang, Chih-Hsin
    Yeh, Kun-Huei
    Hu, Fu-Chang
    Chen, Kuan-Yu
    Shih, Jin-Yuan
    Lin, Zhong-Zhe
    Yu, Chong-Jen
    Cheng, Ann-Lii
    Yang, Pan-Chyr
    [J]. LUNG CANCER, 2009, 64 (03) : 346 - 351
12345