Aspartate β-hydroxylase promotes pancreatic ductal adenocarcinoma metastasis through activation of SRC signaling pathway

被引:0
|
作者
Kosuke Ogawa
Qiushi Lin
Le Li
Xuewei Bai
Xuesong Chen
Hua Chen
Rui Kong
Yongwei Wang
Hong Zhu
Fuliang He
Qinggang Xu
Lianxin Liu
Min Li
Songhua Zhang
Katsuya Nagaoka
Rolf Carlson
Howard Safran
Kevin Charpentier
Bei Sun
Jack Wands
Xiaoqun Dong
机构
[1] Brown University,Liver Research Center, Rhode Island Hospital, Warren Alpert Medical School
[2] The University of Oklahoma Health Sciences Center,Department of Internal Medicine, College of Medicine
[3] The First Affiliated Hospital of Harbin Medical University,Department of Pancreatic and Biliary Surgery; Key Laboratory of Hepatosplenic Surgery, Ministry of Education
[4] Harbin Medical University Cancer Hospital,Department of Internal Medical Oncology
[5] The First Affiliated Hospital of Harbin Medical University,Department of Pathology
[6] Capital Medical University,Department of Interventional Therapy, Beijing Shijitan Hospital
[7] The 9th Affiliated Hospital of Peking University,Institute of Life Sciences
[8] Jiangsu University,Department of Hepatic Surgery, Key Laboratory of Hepatosplenic Surgery, Ministry of Education
[9] The First Affiliated Hospital of Harbin Medical University,Division of Life Sciences and Medicine
[10] The First Affiliated Hospital of USTC,Immunobiology & Transplant Science Center
[11] The University of Sciences and Technology of China,Division of Hematology/Oncology, Rhode Island Hospital/The Miriam Hospital
[12] Houston Methodist Research Institute,Department of Surgery, Rhode Island Hospital
[13] The Warren Alpert Medical School of Brown University,Department of Medicine
[14] The Warren Alpert Medical School of Brown University,undefined
[15] The Warren Alpert Medical School of Brown University,undefined
关键词
Aspartate β-hydroxylase; Invadopodium; Pancreatic ductal adenocarcinoma; Patient-derived xenograft; Metastasis; SRC;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] Increased semaphorin 3c expression promotes tumor growth and metastasis in pancreatic ductal adenocarcinoma by activating the ERK1/2 signaling pathway
    Xu, Xuejun
    Zhao, Zhiping
    Guo, Shixiang
    Li, Jian
    Liu, Songsong
    You, Yu
    Ni, Bing
    Wang, Huaizhi
    Bie, Ping
    CANCER LETTERS, 2017, 397 : 12 - 22
  • [32] Increased Semaphorin 3c Promotes Tumor Growth and Metastasis in Pancreatic Ductal Adenocarcinoma by Inactivating PI3K/AKT Signaling Pathway
    Xu, X.
    Wang, H.
    PANCREAS, 2016, 45 (10) : 1547 - 1547
  • [33] DJ-1 Promotes Invasion and Metastasis of Pancreatic Cancer Cells Through SRC/ERK/uPA Activation
    He Xiangyi
    Yuan, Yao-Zong
    GASTROENTEROLOGY, 2012, 142 (05) : S620 - S620
  • [34] Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma
    Wang, Wulin
    Chen, Hao
    Gao, Wenjie
    Wang, Sheng
    Wu, Kai
    Lu, Chen
    Luo, Xiagang
    Li, Lianhong
    Yu, Chunzhao
    ONCOLOGY REPORTS, 2020, 44 (02) : 637 - 649
  • [35] Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma
    Rama Krishna Nimmakayala
    Frank Leon
    Satyanarayana Rachagani
    Sanchita Rauth
    Palanisamy Nallasamy
    Saravanakumar Marimuthu
    Gautam K. Shailendra
    Yashpal S. Chhonker
    Seema Chugh
    Ramakanth Chirravuri
    Rohitesh Gupta
    Kavita Mallya
    Dipakkumar R. Prajapati
    Subodh M. Lele
    Thomas C. Caffrey
    Jean L. Grem
    Paul M. Grandgenett
    Michael A. Hollingsworth
    Daryl J. Murry
    Surinder K. Batra
    Moorthy P. Ponnusamy
    Oncogene, 2021, 40 : 215 - 231
  • [36] Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma
    Nimmakayala, Rama Krishna
    Leon, Frank
    Rachagani, Satyanarayana
    Rauth, Sanchita
    Nallasamy, Palanisamy
    Marimuthu, Saravanakumar
    Shailendra, Gautam K.
    Chhonker, Yashpal S.
    Chugh, Seema
    Chirravuri, Ramakanth
    Gupta, Rohitesh
    Mallya, Kavita
    Prajapati, Dipakkumar R.
    Lele, Subodh M.
    C. Caffrey, Thomas
    L. Grem, Jean
    Grandgenett, Paul M.
    Hollingsworth, Michael A.
    Murry, Daryl J.
    Batra, Surinder K.
    Ponnusamy, Moorthy P.
    ONCOGENE, 2021, 40 (01) : 215 - 231
  • [37] Complement activation in pancreatic ductal adenocarcinoma
    Bell, Brett I.
    Pandey, Sanjay
    Asp, Patrik
    Guha, Chandan
    CANCER RESEARCH, 2022, 82 (12)
  • [38] FAM84B, amplified in pancreatic ductal adenocarcinoma, promotes tumorigenesis through the Wnt/β-catenin pathway
    Zhang, Xin
    Xu, Jiapeng
    Yan, Ronglin
    Zhang, Yu
    Hu, Zunqi
    Fu, Hongbing
    You, Qing
    Cai, Qingping
    Yang, Dejun
    AGING-US, 2020, 12 (08): : 6808 - 6822
  • [39] GPR120 promotes metastasis but inhibits tumor growth in pancreatic ductal adenocarcinoma
    Sun, Xiaoyuan
    Chu, Huijun
    Lei, Ke
    Ci, Yandong
    Lu, Haijun
    Wang, Jia
    Zhou, Meng
    Ren, He
    Zheng, Tongsen
    PANCREATOLOGY, 2022, 22 (06) : 749 - 759
  • [40] hnRNPAB Promotes Pancreatic Ductal Adenocarcinoma Extravasation and Liver Metastasis by Stabilizing MYC mRNA
    Lei, Ke
    Sun, Mingyue
    Chen, Xianghan
    Wang, Jia
    Liu, Xiaolan
    Ning, Ying
    Ping, Shuai
    Gong, Ruining
    Zhang, Yu
    Qing, Gong
    Zhao, Chenyang
    Ren, He
    MOLECULAR CANCER RESEARCH, 2024, 22 (11) : 1022 - 1035