Advanced strategies for development of vaccines against human bacterial pathogens

被引:0
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作者
Abhinay Sharma
Pooja Sanduja
Aparna Anand
Pooja Mahajan
Carlos A. Guzman
Puja Yadav
Amit Awasthi
Emanuel Hanski
Meenakshi Dua
Atul Kumar Johri
机构
[1] School of Life Sciences,Department of Vaccinology
[2] Jawaharlal Nehru University,Department of Microbiology
[3] School of Environmental Sciences,Department of Microbiology and Molecular Genetics, The Institute for Medical Research, Israel
[4] Jawaharlal Nehru University,Canada (IMRIC), Faculty of Medicine
[5] Helmholtz Centre for Infection Research,undefined
[6] Central University of Haryana,undefined
[7] The Hebrew University of Jerusalem,undefined
[8] Translational Health Science and Technology Institute,undefined
[9] Faridabad—Gurgaon Expressway,undefined
关键词
Genomics; Human pathogens; Protein microarray; Proteomics; Reverse vaccinology; Vaccine;
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摘要
Infectious diseases are one of the main grounds of death and disabilities in human beings globally. Lack of effective treatment and immunization for many deadly infectious diseases and emerging drug resistance in pathogens underlines the need to either develop new vaccines or sufficiently improve the effectiveness of currently available drugs and vaccines. In this review, we discuss the application of advanced tools like bioinformatics, genomics, proteomics and associated techniques for a rational vaccine design.
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