Digital droplet PCR-based quantification of ccfHPV-DNA as liquid biopsy in HPV-driven cervical and vulvar cancer

被引：0
|
作者：
Fabinshy Thangarajah
Jana Busshoff
Janina Salamon
Marie-Sandrine Pruss
Caroline Lenz
Bernd Morgenstern
Martin Hellmich
Hans Anton Schlößer
Maximilian Lenz
Christian Domröse
Michael R. Mallmann
Peter Mallmann
Jonathan Weiß
Fabian Franzen
Sabine Merkelbach-Bruse
Elke Binot
Marie-Lisa Eich
Reinhardt Büttner
Anne Maria Schultheis
Christina Alidousty
机构：
[1] University Hospital of Essen,Department of Gynecology and Obstetrics
[2] University of Duisburg Essen,Department of Obstetrics and Gynecology
[3] Faculty of Medicine,Institute of Medical Statistics, Informatics and Epidemiology
[4] University of Cologne,Center for Molecular Medicine Cologne and Department of General, Visceral and Cancer Surgery
[5] Faculty of Medicine and University Hospital Cologne,Department for Orthopaedic and Trauma Surgery
[6] University of Cologne,Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf
[7] University Hospital of Cologne,Institute of Pathology
[8] Medical Faculty,undefined
[9] University Hospital of Cologne,undefined
[10] Medical Faculty,undefined
[11] University Hospital of Cologne,undefined
[12] Medical Faculty,undefined
[13] University Hospital of Cologne,undefined
[14] Medical Faculty,undefined
来源：
Journal of Cancer Research and Clinical Oncology | 2023年 / 149卷
关键词：
Liquid biopsy; ddPCR; Cervical cancer; Vulvar cancer; cfDNA; cHPV;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：12597 / 12604
页数：7
相关论文
共 50 条
  • [41] Optimization of droplet digital PCR assays for the type-specific detection and quantification of five HPV genotypes, including additional data on viral loads of nine different HPV genotypes in cervical carcinomas
    Malin, Kaliff
    Louise, Bohr Mordhorst
    Gisela, Helenius
    Mats, Karlsson G.
    Gabriella, Lillsunde-Larsson
    JOURNAL OF VIROLOGICAL METHODS, 2021, 294
  • [42] HPV-driven heterogeneity in cervical cancer: study on the role of epithelial cells and myofibroblasts in the tumor progression based on single-cell RNA sequencing analysis
    Zhang, Yunyun
    Zhang, Yu
    Pan, Chenke
    Wang, Wenqian
    Yu, Yao
    PEERJ, 2024, 12
  • [43] Real-time PCR-based system for simultaneous quantification of human papillomavirus types associated with high risk of cervical cancer
    Moberg, M
    Gustavsson, I
    Gyllensten, U
    JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (07) : 3221 - 3228
  • [44] Development of a liquid biopsy based purely quantitative digital droplet PCR assay for detection of MLH-1promoter methylation
    Wang, Danyi
    O'Rourke, Dennis
    Sanchez-Garcia, Jorge F.
    Cai, Ti
    Scheuenpflug, Juergen
    Feng, Zheng
    CANCER RESEARCH, 2020, 80 (16)
  • [45] Digital PCR-based genetic profiling from vitreous fluid as liquid biopsy for primary uveal melanoma: a proof-of-concept study
    R. J. Nell
    M. Versluis
    N. V. Menger
    M. C. Gelmi
    T. H.K. Vu
    R. M. Verdijk
    G. P.M. Luyten
    M. J. Jager
    P. A. van der Velden
    Journal of Experimental & Clinical Cancer Research, 44 (1)
  • [46] Liquid-based cytology and HPV DNA test in anal specimens from women with cervical cancer
    Eleuterio, Jose, Jr.
    Surima, Walyson
    Lima, Matheus A. T.
    Bezerra, Joao V. S.
    Eleuterio, Renata M. N.
    DIAGNOSTIC CYTOPATHOLOGY, 2022, 50 (03) : 99 - 104
  • [47] TRIAGING OF HPV PCR-BASED CERVICAL CANCER SCREENING RESULTS BY INNOVATIVE BIOMARKER MRNA-BASED ASSAYS FOR REDUCTION OF OVER-REFERRAL AND OVERTREATMENT
    Kaufmann, Andreas Martin
    Leenders, William
    Skof, Anna Sophie
    Schreckenberger, Carola
    Ullrich, Andreas
    Sehouli, Jalid
    Gultekin, Murat
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2023, 33 : A69 - A69
  • [48] A comparative study of digital PCR and real-time qPCR for the detection and quantification of HPV mRNA in sentinel lymph nodes of cervical cancer patients
    Carow K.
    Read C.
    Häfner N.
    Runnebaum I.B.
    Corner A.
    Dürst M.
    BMC Research Notes, 10 (1)
  • [49] Digital droplet PCR-based absolute quantification of pre-transplant NPM1 mutation burden predicts relapse in acute myeloid leukemia patients
    Bill, Marius
    Grimm, Juliane
    Jentzsch, Madlen
    Kloss, Laura
    Goldmann, Karoline
    Schulz, Julia
    Beinicke, Stefanie
    Haentschel, Janine
    Cross, Michael
    Vucinic, Vladan
    Poenisch, Wolfram
    Behre, Gerhard
    Franke, Georg-Nikolaus
    Lange, Thoralf
    Niederwieser, Dietger
    Schwind, Sebastian
    ANNALS OF HEMATOLOGY, 2018, 97 (10) : 1757 - 1765
  • [50] Digital droplet PCR-based absolute quantification of pre-transplant NPM1 mutation burden predicts relapse in acute myeloid leukemia patients
    Marius Bill
    Juliane Grimm
    Madlen Jentzsch
    Laura Kloss
    Karoline Goldmann
    Julia Schulz
    Stefanie Beinicke
    Janine Häntschel
    Michael Cross
    Vladan Vucinic
    Wolfram Pönisch
    Gerhard Behre
    Georg-Nikolaus Franke
    Thoralf Lange
    Dietger Niederwieser
    Sebastian Schwind
    Annals of Hematology, 2018, 97 : 1757 - 1765
12345