Subclonal diversification of primary breast cancer revealed by multiregion sequencing

被引：0
|
作者：
Lucy R Yates
Moritz Gerstung
Stian Knappskog
Christine Desmedt
Gunes Gundem
Peter Van Loo
Turid Aas
Ludmil B Alexandrov
Denis Larsimont
Helen Davies
Yilong Li
Young Seok Ju
Manasa Ramakrishna
Hans Kristian Haugland
Peer Kaare Lilleng
Serena Nik-Zainal
Stuart McLaren
Adam Butler
Sancha Martin
Dominic Glodzik
Andrew Menzies
Keiran Raine
Jonathan Hinton
David Jones
Laura J Mudie
Bing Jiang
Delphine Vincent
April Greene-Colozzi
Pierre-Yves Adnet
Aquila Fatima
Marion Maetens
Michail Ignatiadis
Michael R Stratton
Christos Sotiriou
Andrea L Richardson
Per Eystein Lønning
David C Wedge
Peter J Campbell
机构：
[1] Cancer Genome Project,Department of Oncology
[2] Wellcome Trust Sanger Institute,Department of Clinical Science
[3] The University of Cambridge,Department of Oncology
[4] Section of Oncology,Department of Human Genetics
[5] University of Bergen,Department of Surgery
[6] Haukeland University Hospital,Theoretical Division
[7] Breast Cancer Translational Research Laboratory,Department of Pathology
[8] Institut Jules Bordet,Department of Clinical Medicine
[9] Université Libre de Bruxelles,undefined
[10] University of Leuven,undefined
[11] Haukeland University Hospital,undefined
[12] Los Alamos National Laboratory,undefined
[13] Haukeland University Hospital,undefined
[14] The Gade Laboratory for Pathology,undefined
[15] University of Bergen,undefined
[16] Dana-Farber Cancer Institute,undefined
[17] Brigham and Women's Hospital,undefined
[18] Harvard Medical School,undefined
来源：
Nature Medicine | 2015年 / 21卷
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摘要：
Whole-genome and targeted sequencing of multiple sections of each of 50 tumors reveals varying degrees of subclonal diversification and genomic heterogeneity.
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收藏
页码：751 / 759
页数：8
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