Tuning the optical properties of BODIPY dye through Cu(I) catalyzed azide-alkyne cycloaddition (CuAAC) reaction

被引：0
|
作者：
Chao Wang
Fang Xie
Nisaraporn Suthiwangcharoen
Jian Sun
Qian Wang
机构：
[1] Chinese Academy of Sciences,Natural Products Center, Chengdu Institute of Biology
[2] University of South Carolina,Department of Chemistry and Biochemistry
来源：
Science China Chemistry | 2012年 / 55卷
关键词：
CuAAC reaction; fluorogenic; BODIPY dye; cell imaging; fluorescent probe;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Borondipyrromethenes (BODIPY) are a class of fluorescent dyes whose fluorescence quantum yields are generally high and independent of the solvent. In this paper, we report the synthesis of a new type of BODIPY compound that carries an azido group on the 3-position of the pyrrole core. The azido group quenches the fluorescence of the dye due to its weak electron-donating effect. The fluorescence of the BODIPY dye can be switched on after reacting with alkynes via a Cu(I) catalyzed azide-alkyne cycloaddition (CuAAC) reaction. We further demonstrate that this azido-BODIPY compound can be used in the cell imaging applications.
引用
收藏
页码：125 / 130
页数：5
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