A novel sphingosylphosphorylcholine and sphingosine-1-phosphate receptor 1 antagonist, KRO-105714, for alleviating atopic dermatitis

被引：0
|
作者：
Sae-Bom Yoon
Chang Hoon Lee
Hyun Young Kim
Daeyoung Jeong
Moon Kook Jeon
Sun-A Cho
Kwangmi Kim
Taeho Lee
Jung Yoon Yang
Young-Dae Gong
Heeyeong Cho
机构：
[1] Korea Research Institute of Chemical Technology,Drug Discovery Platform Research Center, Therapeutics & Biotechnology Division
[2] Department of Laboratory Animal Medicine,College of Pharmacy
[3] Research Institute for Veterinary Science,Research Institute of Pharmaceutical Sciences, College of Pharmacy
[4] BK21PLUS Program for Creative Veterinary Science Research,Innovative Drug Library Research Center, Science College
[5] College of Veterinary Medicine,Medicinal Chemistry and Pharmacology
[6] Seoul National University,undefined
[7] Danguk University,undefined
[8] Kyungpook National University,undefined
[9] Dongguk University,undefined
[10] Korea University of Science and Technology,undefined
来源：
Journal of Inflammation | / 17卷
关键词：
Sphingosylphosphorylcholine; Sphingosine-1-phosphate receptor 1; Antagonist; Anti-inflammatory; Atopic dermatitis; High-throughput screening;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Role of sphingosine-1-phosphate receptor 1 and sphingosine-1-phosphate receptor 2 in hyperglycemia-induced endothelial cell dysfunction
    Chen, Shuhua
    Yang, Jie
    Xiang, Hong
    Chen, Wei
    Zhong, Hua
    Yang, Guoping
    Fang, Ting
    Deng, Hao
    Yuan, Hong
    Chen, Alex F.
    Lu, Hongwei
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2015, 35 (04) : 1103 - 1108
  • [22] Blockage of sphingosine-1-phosphate receptor 2 attenuates 2,4-dinitrochlorobenzene-induced atopic dermatitis in mice
    Soo-Jin Park
    Dong-Soon Im
    Acta Pharmacologica Sinica, 2020, 41 : 1487 - 1496
  • [23] Local remodeling, mast cell activation and sphingosine-1-phosphate elevation precede atopic dermatitis
    Wedman, P.
    Aladhami, A.
    Chumanevich, A.
    Fuseler, J.
    Oskeritzian, C.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2016, 46 : 98 - 98
  • [24] Sphingosine-1-phosphate receptor signalling in the heart
    Means, Christopher K.
    Brown, Joan Heller
    CARDIOVASCULAR RESEARCH, 2009, 82 (02) : 193 - 200
  • [25] Sphingosine-1-phosphate receptor 3 signaling
    Li, Qian
    Li, Yi
    Lei, Cai
    Tan, Ying
    Yi, Guanghui
    CLINICA CHIMICA ACTA, 2021, 519 : 32 - 39
  • [26] Sphingosine-1-phosphate analogs as receptor antagonists
    Davis, MD
    Clemens, JJ
    Macdonald, TL
    Lynch, KR
    FASEB JOURNAL, 2005, 19 (04): : A525 - A525
  • [27] Antitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma
    Li, Mei-Hong
    Swenson, Rolf
    Harel, Miriam
    Jana, Sampa
    Stolarzewicz, Erik
    Hla, Timothy
    Shapiro, Linda H.
    Ferrer, Fernando
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2015, 354 (03): : 261 - 268
  • [28] Sphingosine-1-phosphate induces in vitro angiogenesis via the sphingosine-1-phosphate receptor 3 and activation of RhoA
    Del Galdo, S.
    Vettel, C.
    Baltus, D.
    Heringdorf, Meyer Zu D.
    Wieland, T.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2011, 383 : 51 - 51
  • [29] Sphingosine-1-phosphate receptor: a novel therapeutic target in ulcerative colitis
    Izzo, Roberta
    Figliuzzi, Michele M.
    Monteleone, Giovanni
    EXPERT REVIEW OF CLINICAL IMMUNOLOGY, 2016, 12 (11) : 1137 - 1139
  • [30] Sphingosine-1-phosphate improves outcome of no-reflow acute myocardial infarction via sphingosine-1-phosphate receptor 1
    Polzin, Amin
    Dannenberg, Lisa
    Benkhoff, Marcel
    Barcik, Maike
    Keul, Petra
    Ayhan, Aysel
    Weske, Sarah
    Ahlbrecht, Samantha
    Trojovsky, Kajetan
    Helten, Carolin
    Haberkorn, Sebastian
    Floegel, Ulrich
    Zeus, Tobias
    Mueller, Tina
    Graeler, Markus H.
    Kelm, Malte
    Levkau, Bodo
    ESC HEART FAILURE, 2023, 10 (01): : 334 - 341
12345