Hypoestoxide reduces neuroinflammation and α-synuclein accumulation in a mouse model of Parkinson’s disease

被引:0
|
作者
Changyoun Kim
Emmanuel Ojo-Amaize
Brian Spencer
Edward Rockenstein
Michael Mante
Paula Desplats
Wolf Wrasidlo
Anthony Adame
Emeka Nchekwube
Olusola Oyemade
Joseph Okogun
Michael Chan
Howard Cottam
Eliezer Masliah
机构
[1] University of California,Department of Neuroscience
[2] University of California,Pathology, School of Medicine
[3] University of California,Moores Cancer Center
[4] Immune Modulation,undefined
[5] Inc.,undefined
来源
Journal of Neuroinflammation | / 12卷
关键词
Hypoestoxide; Parkinson’s disease; Neuroinflammation; Neurodegeneration; α-synuclein; NF-κB;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] β-Amyloid peptides enhance α-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease
    Masliah, E
    Rockenstein, E
    Veinbergs, I
    Sagara, Y
    Mallory, M
    Hashimoto, M
    Mucke, L
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (21) : 12245 - 12250
  • [22] Curcumin reduces α-synuclein induced cytotoxicity in Parkinson's disease cell model
    Min S Wang
    Shanta Boddapati
    Sharareh Emadi
    Michael R Sierks
    BMC Neuroscience, 11
  • [23] Pathological accumulation of α-synuclein and Aβ in Parkinson's disease with dementia
    Campbell, M. C.
    Kotzbauer, P. T.
    Cairns, N. J.
    Racette, B. A.
    Tabbal, S. D.
    Perlmutter, J. S.
    MOVEMENT DISORDERS, 2012, 27 : S62 - S63
  • [24] Necrosulfonamide exerts neuroprotective effect by inhibiting necroptosis, neuroinflammation, and α-synuclein oligomerization in a subacute MPTP mouse model of Parkinson’s disease
    Yea-Hyun Leem
    Do-Yeon Kim
    Jung-Eun Park
    Hee-Sun Kim
    Scientific Reports, 13
  • [25] Necrosulfonamide exerts neuroprotective effect by inhibiting necroptosis, neuroinflammation, and α-synuclein oligomerization in a subacute MPTP mouse model of Parkinson's disease
    Leem, Yea-Hyun
    Kim, Do-Yeon
    Park, Jung-Eun
    Kim, Hee-Sun
    SCIENTIFIC REPORTS, 2023, 13 (01)
  • [26] Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys
    Alarcon-Aris, Diana
    Pavia-Collado, Ruben
    Miquel-Rio, Lluis
    Coppola-Segovia, Valentin
    Ferres-Coy, Albert
    Ruiz-Bronchal, Esther
    Galofre, Mireia
    Paz, Veronica
    Campa, Leticia
    Revilla, Raquel
    Montefeltro, Andres
    Kordower, Jeffrey H.
    Vila, Miquel
    Artigas, Francesc
    Bortolozzi, Analia
    EBIOMEDICINE, 2020, 59
  • [27] Microglia depletion reduces neurodegeneration and remodels extracellular matrix in a mouse Parkinson's disease model triggered by α-synuclein overexpression
    Zhang, Zhen
    Niu, Kun
    Huang, Taoying
    Guo, Jiali
    Xarbat, Gongbikai
    Gong, Xiaoli
    Gao, Yunke
    Liu, Feiyang
    Cheng, Shan
    Su, Wenting
    Yang, Fei
    Liu, Zhaoyuan
    Ginhoux, Florent
    Zhang, Ting
    NPJ PARKINSONS DISEASE, 2025, 11 (01)
  • [28] Age-dependent alpha-synuclein accumulation and aggregation in the colon of a transgenic mouse model of Parkinson’s disease
    Qian-Qian Chen
    Caroline Haikal
    Wen Li
    Ming-Tao Li
    Zhan-You Wang
    Jia-Yi Li
    Translational Neurodegeneration, 7
  • [29] An extended release GLP-1 analogue increases α-synuclein accumulation in a mouse model of prodromal Parkinson's disease
    Bergkvist, Liza
    Johnson, Michaela E.
    Mercado, Gabriela
    Steiner, Jennifer A.
    Meyerdirk, Lindsay
    Schulz, Emily
    Madaj, Zachary
    Ma, Jiyan
    Becker, Katelyn
    Li, Yazhou
    Brundin, Patrik
    EXPERIMENTAL NEUROLOGY, 2021, 341
  • [30] Kurtosis imaging reveals microstructural changes of late-stage -synuclein accumulation in a mouse model of Parkinson's disease
    Williams, Stephen
    JOURNAL OF NEUROCHEMISTRY, 2016, 136 (06) : 1117 - 1118