Spreading and Retention of Vaginal Formulations in Post-Menopausal Women as Assessed by Gamma Scintigraphy

被引：0

作者：

J. Brown

G. Hooper

C. J. Kenyon

S. Haines

J. Burt

J. M. Humphries

S. P. Newman

S. S. Davis

R. A. Sparrow

I. R. Wilding

机构：

[1] Pharmaceutical Profiles Limited,Department of Pharmaceutical Sciences

[2] Nottingham University,Department of Human Morphology

[3] Queen's Medical Centre,undefined

来源：

Pharmaceutical Research | 1997年 / 14卷

关键词：

vaginal delivery; gamma scintigraphy; bioadhesion; pessary; post-menopausal women;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Purpose. In this paper we report on the first scintigraphic evaluation of vaginal dosage forms in post-menopausal women. To date, almost nothing is known about the in vivo performance of pharmaceutical formulations in the human vagina, which is a major deficiency in the rational design of drug delivery systems for both existing and new indications.

引用

页码：1073 / 1078

页数：5

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