Spreading and Retention of Vaginal Formulations in Post-Menopausal Women as Assessed by Gamma Scintigraphy

被引：0
|
作者：
J. Brown
G. Hooper
C. J. Kenyon
S. Haines
J. Burt
J. M. Humphries
S. P. Newman
S. S. Davis
R. A. Sparrow
I. R. Wilding
机构：
[1] Pharmaceutical Profiles Limited,Department of Pharmaceutical Sciences
[2] Nottingham University,Department of Human Morphology
[3] Queen's Medical Centre,undefined
来源：
Pharmaceutical Research | 1997年 / 14卷
关键词：
vaginal delivery; gamma scintigraphy; bioadhesion; pessary; post-menopausal women;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. In this paper we report on the first scintigraphic evaluation of vaginal dosage forms in post-menopausal women. To date, almost nothing is known about the in vivo performance of pharmaceutical formulations in the human vagina, which is a major deficiency in the rational design of drug delivery systems for both existing and new indications.
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页码：1073 / 1078
页数：5
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