Gastric cancer-derived LBP promotes liver metastasis by driving intrahepatic fibrotic pre-metastatic niche formation

被引：0
|
作者：
Li Xie
Shengkui Qiu
Chen Lu
Chao Gu
Jihuan Wang
Jialun Lv
Lang Fang
Zetian Chen
Ying Li
Tianlu Jiang
Yiwen Xia
Weizhi Wang
Bowen Li
Zekuan Xu
机构：
[1] The First Affiliated Hospital of Nanjing Medical University,Department of General Surgery
[2] Nantong First People’s Hospital,Department of General Surgery
[3] Affiliated Hospital 2 of Nantong University,Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine
[4] Nanjing Medical University,undefined
来源：
Journal of Experimental & Clinical Cancer Research | / 42卷
关键词：
Gastric cancer; Secreted proteins; LBP; Liver metastasis; TGF-β1; TLR4; Fibrosis; Pre-metastatic niches;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Colorectal cancer cells-derived exosomal miR-188-3p promotes liver metastasis by creating a pre-metastatic niche via activation of hepatic stellate cells
    Li, Tao
    Li, Taiyuan
    Liang, Yahang
    Yuan, Yuli
    Liu, Yang
    Yao, Yao
    Lei, Xiong
    JOURNAL OF TRANSLATIONAL MEDICINE, 2025, 23 (01)
  • [42] Critical steps to tumor metastasis: alterations of tumor microenvironment and extracellular matrix in the formation of pre-metastatic and metastatic niche
    Jianan Zhuyan
    Mingyu Chen
    Tianhao Zhu
    Xunxia Bao
    Timing Zhen
    Kaichen Xing
    Qiubo Wang
    Sibo Zhu
    Cell & Bioscience, 10
  • [43] IRF5 suppresses metastasis through the regulation of tumor-derived extracellular vesicles and pre-metastatic niche formation
    Roberts, Bailey K.
    Li, Dan Iris
    Somerville, Carter
    Matta, Bharati
    Jha, Vaishali
    Steinke, Adison
    Brune, Zarina
    Blanc, Lionel
    Soffer, Samuel Z.
    Barnes, Betsy J.
    SCIENTIFIC REPORTS, 2024, 14 (01):
  • [44] Non-Coding RNAs Derived from Extracellular Vesicles Promote Pre-Metastatic Niche Formation and Tumor Distant Metastasis
    Cheng, Jin
    Zhang, Kun
    Qu, Chunhui
    Peng, Jinwu
    Yang, Lifang
    CANCERS, 2023, 15 (07)
  • [45] Estrone and prolactin can be markers of risk of metastasis and pre-metastatic niche in patients with stomach cancer
    Kit, O.
    Frantsiyants, E.
    Bandovkina, V.
    Pogorelova, Y.
    Gevorkyan, Y.
    Soldatkina, N.
    Samoylenko, N.
    ANNALS OF ONCOLOGY, 2018, 29
  • [46] Formation of pre-metastatic bone niche in prostate cancer and regulation of traditional chinese medicine
    Chen, Chiwei
    Huang, Renlun
    Zhou, Jianfu
    Guo, Lang
    Xiang, Songtao
    FRONTIERS IN PHARMACOLOGY, 2022, 13
  • [47] KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis
    Murgai, Meera
    Ju, Wei
    Eason, Matthew
    Kline, Jessica
    Beury, Daniel W.
    Kaczanowska, Sabina
    Miettinen, Markku M.
    Kruhlak, Michael
    Lei, Haiyan
    Shern, Jack F.
    Cherepanova, Olga A.
    Owens, Gary K.
    Kaplan, Rosandra N.
    NATURE MEDICINE, 2017, 23 (10) : 1176 - +
  • [48] KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis
    Meera Murgai
    Wei Ju
    Matthew Eason
    Jessica Kline
    Daniel W Beury
    Sabina Kaczanowska
    Markku M Miettinen
    Michael Kruhlak
    Haiyan Lei
    Jack F Shern
    Olga A Cherepanova
    Gary K Owens
    Rosandra N Kaplan
    Nature Medicine, 2017, 23 : 1176 - 1190
  • [49] Tumor-Secreted GRP78 Promotes the Establishment of a Pre-metastatic Niche in the Liver Microenvironment
    Chen, Lu
    Zheng, Hao
    Yu, Xiang
    Liu, Lei
    Li, Heli
    Zhu, Huifen
    Zhang, Zhihong
    Lei, Ping
    Shen, Guanxin
    FRONTIERS IN IMMUNOLOGY, 2020, 11
  • [50] Colorectal cancer-derived extracellular vesicles induce liver premetastatic immunosuppressive niche formation to promote tumor early liver metastasis
    Xuyang Yang
    Yaguang Zhang
    Yang Zhang
    Huifang Li
    Li Li
    Yangping Wu
    Xiangzheng Chen
    Lei Qiu
    Junhong Han
    Ziqiang Wang
    Signal Transduction and Targeted Therapy, 8
12345