The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic syndrome

被引:0
|
作者
Vanesa Stepanov
Karmen Stankov
Momir Mikov
机构
[1] University of Novi Sad,Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine
[2] University of Novi Sad,Clinical Centre of Vojvodina, Faculty of Medicine
关键词
Metabolic Syndrome; Bile Acid; Brown Adipose Tissue; Liver Steatosis; Pharmacological Target;
D O I
10.1186/2050-6511-13-S1-A7
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] Expression and function of the bile acid receptor TGR5 in Kupffer cells
    Keitel, Verena
    Donner, Markus
    Winandy, Stefanie
    Kubitz, Ralf
    Haeussinger, Dieter
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 372 (01) : 78 - 84
  • [32] ALCOHOL CONSUMPTION IN MICE LACKING THE BILE ACID RECEPTOR TGR5
    Ferrell, Jessica
    Dilts, Matthew
    Boehme, Shannon
    Pokhrel, Sabita
    Olotu, Titilayo
    Ferdous, Shifat-e
    HEPATOLOGY, 2024, 80 : S1576 - S1576
  • [33] Distribution of bile acid receptor TGR5 in the gastrointestinal tract of dogs
    Giaretta, Paula R.
    Suchodolski, Jan S.
    Blick, Anna K.
    Steiner, Joerg M.
    Lidbury, Jonathan A.
    Rech, Raquel R.
    HISTOLOGY AND HISTOPATHOLOGY, 2019, 34 (01) : 69 - 79
  • [34] Essential roles of bile acid receptors FXR and TGR5 as metabolic regulators
    Jacinto, Sandra
    Fang, Sungsoon
    ANIMAL CELLS AND SYSTEMS, 2014, 18 (06) : 359 - 364
  • [35] Expression and localization of the membrane-bound bile acid receptor TGR5 in human gallbladder tissue
    Keitel, V.
    Cupisti, K.
    Kubitz, R.
    Haeussinger, D.
    BILE ACID BIOLOGY AND THERAPEUTIC ACTIONS, 2009, 165 : 82 - 85
  • [36] Membrane bile acid receptor TGR5 predicts good prognosis in ampullary adenocarcinoma patients with hyperbilirubinemia
    Chen, Min-Chan
    Chen, Yi-Ling
    Wang, Tzu-Wen
    Hsu, Hui-Ping
    Lai, Ming-Derg
    ONCOLOGY REPORTS, 2016, 36 (04) : 1997 - 2008
  • [37] The role of bile acids and their TGR5 receptor in irritable bowel syndrome and diarrhoea
    Walters, Julian R. F.
    DIGESTIVE AND LIVER DISEASE, 2021, 53 (09) : 1118 - 1119
  • [38] The bile-acid receptor TGR5 regulates biliary epithelium permeability
    Ursic-Bedoya, Jose
    Simerabet, Hayat
    Doignon, Isabelle
    Pean, Noemie
    Tanfin, Zahra
    Ullmer, Christoph
    Humbert, Lydie
    Rainteau, Dominique
    Cassio, Doris
    Tordjmann, Thierry
    HEPATOLOGY, 2015, 62 : 615A - 615A
  • [39] Expression and Function of Bile Acid Receptor TGR5 in Gastrointestinal Smooth Muscle
    Rajagopal, Senthilkumar
    Al-Shboul, Othman
    Mahavadi, Sunila
    Kuemmerle, John F.
    Murthy, Karnam S.
    FASEB JOURNAL, 2011, 25
  • [40] THE BILE ACID RECEPTOR TGR5 AND DIET-INDUCED LIVER INJURY
    Ferrell, Jessica M.
    Dilts, Matthew
    Stahl, Zachary
    Boehme, Shannon
    Dey, Shreya
    Chiang, John Y. L.
    HEPATOLOGY, 2021, 74 : 278A - 278A