New antiplatelet therapies for acute coronary syndromes

被引：2
|
作者：
Rich J.D. [1 ]
Wiviott S.D. [1 ]
机构：
[1] Cardiovascular Division, Brigham and Women's Hospital, TIMI Study Group, Boston
来源：
Current Cardiology Reports | 2007年 / 9卷 / 4期
关键词：
Percutaneous Coronary Intervention; Acute Coronary Syndrome; Clopidogrel; Abciximab; P2Y12 Receptor;
D O I：
10.1007/BF02938379
中图分类号：
学科分类号：
摘要：
Platelets play a central role in the pathophysiology of acute coronary syndromes (ACS). Dual antiplatelet therapy has resulted in significant advances in the treatment of ACS; however, ACS remains an important cause of morbidity and mortality. Important limitations exist among the current antiplatelet agents and therefore a pressing need for the development of improved antiplatelet agents exists. Three antiplatelet agents currently under investigation (prasugrel, AZD6140, and cangrelor) in clinical trials for the treatment of ACS appear promising. Copyright © 2007 by Current Medicine Group LLC.
引用
收藏
页码：303 / 311
页数：8
相关论文
共 50 条
  • [31] New Antiplatelet Agents and the Role of Platelet Function Testing in Acute Coronary Syndromes
    Sinhal, Ajay R.
    Aylward, Philip E.
    CLINICAL THERAPEUTICS, 2013, 35 (08) : 1064 - 1068
  • [32] Optimal antiplatelet and anticoagulation strategies in acute coronary syndromes
    Rath, Dominik
    Geisler, Tobias
    HERZ, 2020, 45 (06) : 528 - 536
  • [33] Novel antiplatelet targets in the treatment of acute coronary syndromes
    Alenazy, Fawaz O.
    Thomas, Mark R.
    PLATELETS, 2021, 32 (01) : 15 - 28
  • [34] Antiplatelet therapy for elderly patients with Acute Coronary Syndromes
    Savonitto, Stefano
    Morici, Nuccia
    De Servi, Stefano
    AGING-US, 2018, 10 (09): : 2220 - 2221
  • [35] Antiplatelet therapy in acute coronary syndromes: focus on ticagrelor
    Birkeland, Kade
    Parra, David
    Rosenstein, Robert
    JOURNAL OF BLOOD MEDICINE, 2010, 1 : 197 - 219
  • [36] Antiplatelet options for secondary prevention in acute coronary syndromes
    Silvain, Johanne
    Cayla, Guillaume
    O'Connor, Stephen A.
    Collet, Jean-Philippe
    Montalescot, Gilles
    EXPERT REVIEW OF CARDIOVASCULAR THERAPY, 2011, 9 (11) : 1403 - 1415
  • [37] Use of Novel Antiplatelet Agents in Acute Coronary Syndromes
    Michael Luna
    Elizabeth M. Holper
    Current Atherosclerosis Reports, 2015, 17
  • [38] Contemporary Antiplatelet Pharmacotherapy in the Management of Acute Coronary Syndromes
    Mangels D.R.
    Nathan A.
    Tuteja S.
    Giri J.
    Kobayashi T.
    Current Treatment Options in Cardiovascular Medicine, 2018, 20 (2)
  • [39] Platelet aggregation and antiplatelet agents in acute coronary syndromes
    Collet, JP
    Choussat, M
    Montalescot, G
    M S-MEDECINE SCIENCES, 2004, 20 (03): : 291 - +
  • [40] Acute coronary syndromes: 2. Antiplatelet agents
    Schneider, DJ
    Tracy, PB
    Sobel, BE
    HOSPITAL PRACTICE, 1998, 33 (05) : 107 - +
12345