Effects of cilostazol on lipid and fatty acid metabolism

被引：0
|
作者：
N. Nakamura
H. Osawa
H. Yamabe
K. Okumura
T. Hamazaki
机构：
[1] Hirosaki University School of Medicine,The Second Department of Internal Medicine
[2] Toyama Medical and Pharmaceutical University,Department of Clinical Sciences, Institute of Natural Medicine
来源：
Clinical and Experimental Medicine | 2005年 / 4卷
关键词：
Cilostazol; Docosahexaenoic acid; Polyunsaturated fatty acid; Serum lipid;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Cilostazol is a selective inhibitor of phosphodiesterase III with anti-platelet-aggregatory and vasodilating properties. Randomised, double-blind, placebo-controlled trials in 2702 patients with intermittent claudication demonstrated that cilostazol significantly increased walking distances compared with placebo. Furthermore, the agent has beneficial effects on the serum lipid profile and fatty acid composition in plasma. Consequently, cilostazol may be useful to prevent atherosclerosis from progressing by ameliorating lipid and fatty acid metabolism.
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页码：170 / 173
页数：3
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