Degradation and miscibility of poly(DL-lactic acid)/poly(glycolic acid) composite films: Effect of poly(DL-lactic-co-glycolic acid)

被引：0
|
作者：
ZHIGANG MA
NA ZHAO
CHENGDONG XIONG
机构：
[1] Huangshi Institute of Technology,School of Chemical and Material Engineering
[2] Chinese Academy of Sciences,Chengdu Organic Chemicals Co. Ltd.
来源：
Bulletin of Materials Science | 2012年 / 35卷
关键词：
Polymers; composite materials; thin films; microstructure; compatibility;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The in vitro degradation behaviour of poly(glycolic acid) (PGA) and its composite films containing poly(DL-lactic acid) (PDLLA) and poly(DL-lactic-co-glycolic acid) (PDLGA) were investigated via mass loss, scanning electron microscopy (SEM) and differential scanning calorimetry (DSC). All the films were prepared by solution casting, using 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) as the solvent. Since the degradation rate of PDLLA is lower than that of PGA, those of the PDLLA/PGA composite films decreased. As a compatibilizer, PDLGA improved the compatibility and hydrolytic stability of PDLLA/PGA composite films. Changes in the composite films indicate that this kind of PGA-based composite biomaterial may be applicable to device design for clinical application in the future.
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页码：575 / 578
页数：3
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