Linking oncogenic pathways with therapeutic opportunities

被引：0
|
作者：
Andrea H. Bild
Anil Potti
Joseph R. Nevins
机构：
[1] the Duke Institute for Genome Sciences and Policy,
[2] Duke University Medical Center,undefined
来源：
Nature Reviews Cancer | 2006年 / 6卷
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D O I：
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中图分类号：
学科分类号：
摘要：
Multiple mutations and alterations in the cancer genome lead to the deregulation of various cell-signalling pathways that control cell function. Can molecular-profiling studies be used to fully understand this complexity and provide an opportunity to link pathway deregulation with potential therapeutic strategies?
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页码：735 / 741
页数：6
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