The clinical implications of medulloblastoma subgroups

被引:0
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作者
Paul A. Northcott
Andrey Korshunov
Stefan M. Pfister
Michael D. Taylor
机构
[1] German Cancer Research Center (DKFZ),Division Molecular Genetics
[2] Clinical Cooperation Unit,undefined
[3] Neuropathology,undefined
[4] German Cancer Research Center (DKFZ),undefined
[5] The Arthur & Sonia Labatt Brain Tumor Research Centre,undefined
[6] Hospital for Sick Children,undefined
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摘要
Medulloblastoma, once thought to represent a single disease entity, is now recognized to comprise distinct subgroups that can be identified using histological, genetic and transcriptomic approaches. Northcott et al. present the evidence for the four recently defined subgroups of medulloblastoma, and highlight how stratification of tumours into these subgroups could have important clinical implications for patient prognosis, treatment and care.
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页码:340 / 351
页数:11
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