Safety and Biodistribution of Human Bone Marrow-Derived Mesenchymal Stromal Cells Injected Intrathecally in Non-Obese Diabetic Severe Combined Immunodeficiency Mice: Preclinical Study

被引：0
|
作者：
Mari Paz Quesada
David García-Bernal
Diego Pastor
Alicia Estirado
Miguel Blanquer
Ana Mª García-Hernández
José M. Moraleda
Salvador Martínez
机构：
[1] Campus of International Excellence “Campus Mare Nostrum” University of Murcia,Cellular Therapy and Hematopoietic Transplant Unit, Hematology Department, Virgen de la Arrixaca Clinical University Hospital, Biomedical Research Institute of Murcia, IMIB
[2] University of Murcia,Arrixaca
[3] Virgen de la Arrixaca Clinical University Hospital,Internal Medicine Department, Medicine School
[4] University Miguel Hernández of Elche,Sport Research Center
[5] University Miguel Hernández of Elche,Neuroscience Institute UMH
[6] CIBERSAM-ISCIII,CSIC
[7] University Miguel Hernández of Elche,Human Anatomy Department, Medicine School
来源：
Tissue Engineering and Regenerative Medicine | 2019年 / 16卷
关键词：
Intrathecal transplantation; Bone marrow-derived mesenchymal stromal cells; Friedreich’s Ataxia; Neuroprotection; Preclinical study;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：525 / 538
页数：13
相关论文
共 50 条
  • [31] Conditioned Medium of Bone Marrow-Derived Mesenchymal Stromal Cells as a Therapeutic Approach to Neuropathic Pain: A Preclinical Evaluation
    Gama, Kelly Barbosa
    Santos, Dourivaldo Silva
    Evangelista, Afranio Ferreira
    Silva, Daniela Nascimento
    de Alcantara, Adriano Costa
    dos Santos, Ricardo Ribeiro
    Pereira Soares, Milena Botelho
    Villarreal, Cristiane Flora
    STEM CELLS INTERNATIONAL, 2018, 2018
  • [32] Differential Immunomodulatory Effects of Human Bone Marrow-Derived Mesenchymal Stromal Cells on Natural Killer Cells
    Hu, Chia-Hsuan Donna
    Kosaka, Yoko
    Marcus, Paula
    Rashedi, Iran
    Keating, Armand
    STEM CELLS AND DEVELOPMENT, 2019, 28 (14) : 933 - 943
  • [33] Effects of dextran on proliferation and osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells
    Li, D.
    Dai, K.
    Tang, T.
    CYTOTHERAPY, 2008, 10 (06) : 587 - 596
  • [34] Osteogenic Potential of Human Bone Marrow-Derived Mesenchymal Stromal Cells Cultured in Autologous Serum: A Preliminary Study
    Takeda, Akira
    Yamazaki, Yasuharu
    Baba, Kyoko
    Ishiguro, Masashi
    Aoyagi, Kazuya
    Ikemoto, Shigehiro
    Uchinuma, Eiju
    JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2012, 70 (08) : E469 - E476
  • [35] Human Term Placenta-Derived Mesenchymal Stromal Cells Are Less Prone to Osteogenic Differentiation Than Bone Marrow-Derived Mesenchymal Stromal Cells
    Pilz, Gregor A.
    Ulrich, Christine
    Ruh, Manuel
    Abele, Harald
    Schaefer, Richard
    Kluba, Torsten
    Buehring, Hans-Joerg
    Rolauffs, Bernd
    Aicher, Wilhelm K.
    STEM CELLS AND DEVELOPMENT, 2011, 20 (04) : 635 - 646
  • [36] In utero transplantation of human bone marrow-derived multipotent mesenchymal stem cells in mice
    Chou, SH
    Kuo, TK
    Liu, M
    Lee, OK
    JOURNAL OF ORTHOPAEDIC RESEARCH, 2006, 24 (03) : 301 - 312
  • [37] Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency
    Starc, Nadia
    Ingo, Daniela
    Conforti, Antonella
    Rossella, Valeria
    Tomao, Luigi
    Pitisci, Angela
    De Mattia, Fabiola
    Brigida, Immacolata
    Algeri, Mattia
    Montanari, Mauro
    Palumbo, Giuseppe
    Merli, Pietro
    Rossi, Paolo
    Aiuti, Alessandro
    Locatelli, Franco
    Bernardo, Maria Ester
    SCIENTIFIC REPORTS, 2017, 7
  • [38] Efficacy and safety of adult human bone marrow-derived, cultured, pooled, allogeneic mesenchymal stromal cells (Stempeucel®): preclinical and clinical trial in osteoarthritis of the knee joint
    Gupta, Pawan Kumar
    Chullikana, Anoop
    Rengasamy, Mathiyazhagan
    Shetty, Naresh
    Pandey, Vivek
    Agarwal, Vikas
    Wagh, Shrikant Yeshwant
    Vellotare, Prasanth Kulapurathu
    Damodaran, Devi
    Viswanathan, Pachaiyappan
    Thej, Charan
    Balasubramanian, Sudha
    Sen Majumdar, Anish
    ARTHRITIS RESEARCH & THERAPY, 2016, 18
  • [39] Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency
    Nadia Starc
    Daniela Ingo
    Antonella Conforti
    Valeria Rossella
    Luigi Tomao
    Angela Pitisci
    Fabiola De Mattia
    Immacolata Brigida
    Mattia Algeri
    Mauro Montanari
    Giuseppe Palumbo
    Pietro Merli
    Paolo Rossi
    Alessandro Aiuti
    Franco Locatelli
    Maria Ester Bernardo
    Scientific Reports, 7
  • [40] Efficacy and safety of adult human bone marrow-derived, cultured, pooled, allogeneic mesenchymal stromal cells (Stempeucel®): preclinical and clinical trial in osteoarthritis of the knee joint
    Pawan Kumar Gupta
    Anoop Chullikana
    Mathiyazhagan Rengasamy
    Naresh Shetty
    Vivek Pandey
    Vikas Agarwal
    Shrikant Yeshwant Wagh
    Prasanth Kulapurathu Vellotare
    Devi Damodaran
    Pachaiyappan Viswanathan
    Charan Thej
    Sudha Balasubramanian
    Anish Sen Majumdar
    Arthritis Research & Therapy, 18
12345