Biological evaluations and spectroscopic characterizations of 3-(4-ethoxyphenyl)-2-methylacrylate based organotin(IV) carboxylates derivatives

被引：0
|
作者：
M. Tariq
M. Sirajuddin
S. Ali
N. Khalid
N. A. Shah
机构：
[1] Bahauddin Zakariya University,Institute of Chemical Sciences
[2] University of Science and Technology,Department of Chemistry
[3] Quaid-i-Azam University,Department of Chemistry
[4] Pakistan Institute of Nuclear Science and Technology,Chemistry Division
[5] COMSATS Institute of Information Technology,Department of Biosciences
来源：
Russian Journal of General Chemistry | 2017年 / 87卷
关键词：
organotin(IV) carboxylate; antibacterial activity; antifungal activity; DNA binding study;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Six new organotin(IV) carboxylates, [Me2SnL2] (1), [n-Bu2SnL2] (2), [n-Oct2SnL2] (3), [Me3SnL] (4), [n-Bu3SnL] (5) and [Ph3SnL] (6), where L = 3-(4-ethoxyphenyl)-2-methylacrylate, have been synthesized and characterized by FT-IR, NMR spectroscopy and elemental analyses. The synthesized compounds were tested for in vitro antibacterial and antifungal activities. The complexes 4–6 demonstrated higher activity than the complexes 1–3. UV-Vis absorption spectroscopy indicated that the ligand and its complexes interacted with DNA via partial intercalation as well as minor groove binding.
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页码：2690 / 2698
页数：8
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