Three-dimensional gradient porous polymeric composites for osteochondral regeneration

被引：0
|
作者：
Elnaz Tamjid
Shadi Marzooghi
Parvin Najafi
Mehrdad Behmanesh
机构：
[1] Tarbiat Modares University,Department of Nanobiotechnology, Faculty of Biological Sciences
[2] Tarbiat Modares University,Department of Biomaterials, Faculty of Interdisciplinary Science and Technology
[3] Tarbiat Modares University,Department of Genetics, Faculty of Biological Sciences
来源：
Journal of Polymer Research | 2022年 / 29卷
关键词：
Gradient pore structure; Additive manufacturing; Geometrical stimulation, Osteochondral engineering;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Poly (ε-caprolactone, PCL) matrix composite scaffolds with controlled gradient pore structure (GPS) were prepared by 3D printing. It is shown that GPS stimulates the osteogenic and chondrogenic differentiation of mesenchymal stem cells (MSCs) in vitro. Curvature-assisted biomineralization and the effect of pore sizes are elaborated. Different effects of nanobioceramics (Bioglass and Titania) on the cell differentiation and tissue-ingrowth kinetics are reported. The fabricated GPS biomaterials by additive manufacturing could provide a new pathway for osteochondral regeneration.
引用
收藏
相关论文
共 50 条
  • [1] Three-dimensional gradient porous polymeric composites for osteochondral regeneration
    Tamjid, Elnaz
    Marzooghi, Shadi
    Najafi, Parvin
    Behmanesh, Mehrdad
    JOURNAL OF POLYMER RESEARCH, 2022, 29 (05)
  • [2] THREE-DIMENSIONAL PRINTING OF LITHIUM-DOPED CALCIUM SILICATE POROUS SCAFFOLD FOR OSTEOCHONDRAL REGENERATION
    Chou, Yun-Ting
    Lin, Yeng-Hong
    Lin, Tsung-Li
    Shie, Ming-You
    TISSUE ENGINEERING PART A, 2022, 28 : S53 - S54
  • [3] Development of Novel Three-Dimensional Printed Scaffolds for Osteochondral Regeneration
    Holmes, Benjamin
    Zhu, Wei
    Li, Jiaoyan
    Lee, James D.
    Zhang, Lijie Grace
    TISSUE ENGINEERING PART A, 2015, 21 (1-2) : 403 - 415
  • [4] Biomechanical Aspects of Osteochondral Regeneration: Implications and Strategies for Three-Dimensional Bioprinting
    Choe, Robert
    Devoy, Eoin
    Jabari, Erfan
    Packer, Jonathan D.
    Fisher, John P.
    TISSUE ENGINEERING PART B-REVIEWS, 2022, 28 (04) : 766 - 788
  • [5] Functionally gradient three-dimensional graphene foam-based polymeric scaffolds for multilayered tissue regeneration
    Gupta, Pallavi
    Waghmare, Sonali
    Kar, Srabani
    Illath, Kavitha
    Rao, Suresh
    Santra, Tuhin Subhra
    RSC ADVANCES, 2023, 13 (02) : 1245 - 1255
  • [6] Osteochondral Repair Using Porous Three-dimensional Nanocomposite Scaffolds in a Rabbit Model
    Zylinska, Beata
    Stodolak-Zych, Ewa
    Sobczynska-Rak, Aleksandra
    Szponder, Tomasz
    Silmanowicz, Piotr
    Lancut, Miroslaw
    Jarosz, Lukasz
    Rozanski, Pawel
    Polkowska, Izabela
    IN VIVO, 2017, 31 (05): : 895 - 903
  • [7] Three-dimensional bioprinting biphasic multicellular living scaffold facilitates osteochondral defect regeneration
    Yu, Xingge
    Gholipourmalekabadi, Mazaher
    Wang, Xudong
    Yuan, Changyong
    Lin, Kaili
    INTERDISCIPLINARY MATERIALS, 2024,
  • [8] Three-dimensional macroscopic scaffolds with a gradient in stiffness for functional regeneration of interfacial tissues
    Singh, Milind
    Dormer, Nathan
    Salash, Jean R.
    Christian, Jordan M.
    Moore, David S.
    Berkland, Cory
    Detamore, Michael S.
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2010, 94A (03) : 870 - 876
  • [9] Three-Dimensional Porous Biodegradable Polymeric Scaffolds Fabricated with Biodegradable Hydrogel Porogens
    Kim, Jinku
    Yaszemski, Michael J.
    Lu, Lichun
    TISSUE ENGINEERING PART C-METHODS, 2009, 15 (04) : 583 - 594
  • [10] Three-Dimensional Convection in an Inclined Porous Layer Subjected to a Vertical Temperature Gradient
    Shubenkov, Ivan
    Lyubimova, Tatyana
    Sadilov, Evgeny
    FDMP-FLUID DYNAMICS & MATERIALS PROCESSING, 2024, 20 (09): : 1957 - 1970
12345