Whole-genome fingerprint of the DNA methylome during human B cell differentiation

被引：0

作者：

Marta Kulis

Angelika Merkel

Simon Heath

Ana C Queirós

Ronald P Schuyler

Giancarlo Castellano

Renée Beekman

Emanuele Raineri

Anna Esteve

Guillem Clot

Néria Verdaguer-Dot

Martí Duran-Ferrer

Nuria Russiñol

Roser Vilarrasa-Blasi

Simone Ecker

Vera Pancaldi

Daniel Rico

Lidia Agueda

Julie Blanc

David Richardson

Laura Clarke

Avik Datta

Marien Pascual

Xabier Agirre

Felipe Prosper

Diego Alignani

Bruno Paiva

Gersende Caron

Thierry Fest

Marcus O Muench

Marina E Fomin

Seung-Tae Lee

Joseph L Wiemels

Alfonso Valencia

Marta Gut

Paul Flicek

Hendrik G Stunnenberg

Reiner Siebert

Ralf Küppers

Ivo G Gut

Elías Campo

José I Martín-Subero

机构：

[1] Institut d'Investigacions Biomédiques August Pi i Sunyer (IDIBAPS),Department of Anatomic Pathology

[2] Pharmacology and Microbiology,Department of Laboratory Medicine

[3] University of Barcelona,Department of Laboratory Medicine

[4] Centro Nacional de Análisis Genómico (CNAG),Department of Epidemiology and Biostatistics

[5] Parc Científic de Barcelona,undefined

[6] Structural Biology and Biocomputing Program,undefined

[7] Spanish National Cancer Research Centre (CNIO),undefined

[8] Spanish National Bioinformatics Institute,undefined

[9] European Molecular Biology Laboratory–European Bioinformatics Institute (EMBL-EBI),undefined

[10] Wellcome Trust Genome Campus,undefined

[11] Area de Oncología,undefined

[12] Centro de Investigación Médica Aplicada (CIMA),undefined

[13] Universidad de Navarra,undefined

[14] Servicio de Hematología,undefined

[15] Clínica Universidad de Navarra,undefined

[16] Flow Cytometry Core,undefined

[17] Centro de Investigación Médica Aplicada (CIMA),undefined

[18] Universidad de Navarra,undefined

[19] Université de Rennes 1,undefined

[20] INSERM U917,undefined

[21] Hematology Laboratory,undefined

[22] University Hospital of Rennes,undefined

[23] Blood Systems Research Institute,undefined

[24] University of California,undefined

[25] San Francisco,undefined

[26] Yonsei University College of Medicine,undefined

[27] University of California,undefined

[28] San Francisco,undefined

[29] Molecular Biology,undefined

[30] Nijmegen Centre for Molecular Life Sciences (NCMLS),undefined

[31] Faculties of Science and Medicine,undefined

[32] Radboud University,undefined

[33] Institute of Human Genetics,undefined

[34] Christian Albrechts University,undefined

[35] Institute of Cell Biology (Cancer Research),undefined

[36] Medical School,undefined

[37] University of Duisburg-Essen,undefined

来源：

Nature Genetics | 2015年 / 47卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

José Martín-Subero and colleagues report the whole-genome bisulfite sequencing of ten blood cell subpopulations representing the cellular stages during B cell differentiation. They find that early stages are characterized by enhancer demethylation and that neoplasms derived from B cell lineages undergo methylation changes in regions with dynamic methylation during normal differentiation.

引用

页码：746 / 756

页数：10

共 50 条

[1] Whole-genome fingerprint of the DNA methylome during human B cell differentiation
Kulis, Marta
Merkel, Angelika
Heath, Simon
Queiros, Ana C.
Schuyler, Ronald P.
Castellano, Giancarlo
Beekman, Renee
Raineri, Emanuele
Esteve, Anna
Clot, Guillem
Verdaguer-Dot, Nuria
Duran-Ferrer, Marti
Russinol, Nuria
Vilarrasa-Blasi, Roser
Ecker, Simone
Pancaldi, Vera
Rico, Daniel
Agueda, Lidia
Blanc, Julie
Richardson, David
Clarke, Laura
Datta, Avik
Pascual, Marien
Agirre, Xabier
Prosper, Felipe
Alignani, Diego
Paiva, Bruno
Caron, Gersende
Fest, Thierry
Muench, Marcus O.
Fomin, Marina E.
Lee, Seung-Tae
Wiemels, Joseph L.
Valencia, Alfonso
Gut, Marta
Flicek, Paul
Stunnenberg, Hendrik G.
Siebert, Reiner
Kueppers, Ralf
Gut, Ivo G.
Campo, Elias
Martin-Subero, Jose I.
NATURE GENETICS, 2015, 47 (07) : 746 - +
[2] Whole-genome fingerprint of the DNA methylome during chemically induced differentiation of the human AML cell line HL-60/S4
Antwi, Enoch B.
Olins, Ada
Teif, Vladimir B.
Bieg, Matthias
Bauer, Tobias
Gu, Zuguang
Brors, Benedikt
Eils, Roland
Olins, Donald
Ishaque, Naveed
BIOLOGY OPEN, 2020, 9 (02):
[3] Characterization of the DNA Methylome during Human B-Cell Differentiation
Kulis, Marta
Heath, Simon
Castellano, Giancarlo
Beekman, Renee
Merkel, Angelika
Raineri, Emanuele
Esteve, Anna
Queiros, Ana C.
Clot, Guillem
Schuyler, Ronald
Ecker, Simone
Pancaldi, Vera
Rico, Daniel
Agueda, Lidia
Blanc, Julie
Richardson, David
Clarke, Laura
Datta, Avik
Russinol, Nuria
Pascual, Marien
Aguirre, Xavier
Prosper, Felipe
Alignani, Diego
Paiva, Bruno
Caron, Gersende
Fest, Thierry
Muench, Marcus O.
Fomin, Marina
Lee, Seung-Tae
Wiemels, Joseph L.
Valencia, Alfonso
Gut, Marta
Flicek, Paul
Stunnenberg, Hendrik G.
Siebert, Reiner
Kueppers, Ralf
Gut, Ivo G.
Campo, Elias
Martin-Subero, Jose I.
BLOOD, 2014, 124 (21)
[4] Whole-Genome DNA Methylation Dynamics of Sheep Preimplantation Embryo Investigated by Single-Cell DNA Methylome Sequencing
Zhang, Zijing
Xu, Jiawei
Lyu, Shijie
Xin, Xiaoling
Shi, Qiaoting
Huang, Yongzhen
Yu, Xiang
Zhu, Xiaoting
Li, Zhiming
Wang, Xianwei
Lang, Limin
Xu, Zhaoxue
Wang, Eryao
FRONTIERS IN GENETICS, 2021, 12
[5] A noninvasive method for whole-genome skin methylome profiling
Banila, Cristiana
Green, Daniel
Katsanos, Dimitris
Viana, Joana
Osmaston, Alice
Vazquez, Angel Menendez
Lynch, Magnus
Kaveh, Shakiba
BRITISH JOURNAL OF DERMATOLOGY, 2023, 189 (06) : 750 - 759
[6] Whole-genome DNA sequencing
Myers, G
COMPUTING IN SCIENCE & ENGINEERING, 1999, 1 (03) : 33 - 43
[7] Cell-Cycle-Dependent Reconfiguration of the DNA Methylome during Terminal Differentiation of Human B Cells into Plasma Cells
Caron, Gersende
Hussein, Mourad
Kulis, Marta
Delaloy, Celine
Chatonnet, Fabrice
Pignarre, Amandine
Avner, Stephane
Lemarie, Maud
Mahe, Elise A.
Verdaguer-Dot, Nuria
Queiros, Ana C.
Tarte, Karin
Martin-Subero, Jose I.
Salbert, Gilles
Fest, Thierry
CELL REPORTS, 2015, 13 (05): : 1059 - 1071
[8] Whole-genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver
Li, Xin
Liu, Yun
Salz, Tal
Hansen, Kasper D.
Feinberg, Andrew
GENOME RESEARCH, 2016, 26 (12) : 1730 - 1741
[9] Whole-genome patterns of common DNA variation in three human populations
Hinds, DA
Stuve, LL
Nilsen, GB
Halperin, E
Eskin, E
Ballinger, DG
Frazer, KA
Cox, DR
SCIENCE, 2005, 307 (5712) : 1072 - 1079
[10] Cancer detection using whole-genome sequencing of cell free DNA
Leary, Rebecca J.
Sausen, Mark
Diaz, Luis A., Jr.
Velculescu, Victor E.
ONCOTARGET, 2013, 4 (08) : 1119 - 1120

← 1 2 3 4 5 →