Expression of ER stress markers (GRP78 and PERK) in experimental nephrotoxicity induced by cisplatin and gentamicin: roles of inflammatory response and oxidative stress

被引：0
|
作者：
Tuba Ozcan Metin
Gulsen Bayrak
Selma Yaman
Adem Doganer
Atila Yoldas
Nadire Eser
Duygun Altintas Aykan
Banu Coskun Yilmaz
Akif Hakan Kurt
Lokman Ayaz
Mehmet Sahin
机构：
[1] Kahramanmaras Sutcu Imam University,Department of Histology and Embryology, Faculty of Medicine
[2] Usak University,Department of Histology and Embryology, Faculty of Medicine
[3] Kahramanmaras Sutcu Imam University,Department of Biophysics, Faculty of Medicine
[4] Kahramanmaras Sutcu Imam University,Department of Biostatistics and Medical Informatics, Faculty of Medicine
[5] Kahramanmaras Sutcu Imam University,Department of Anatomy, Faculty of Medicine
[6] Kahramanmaras Sutcu Imam University,Department of Pharmacology, Faculty of Medicine
[7] Mersin University,Department of Histology and Embryology, Faculty of Medicine
[8] Bolu Abant Izzet Baysal University,Department of Pharmacology, Faculty of Medicine
[9] Trakya University,Department of Biochemistry, Faculty of Pharmacy
[10] Gaziantep University,Department of Medical Biology, Faculty of Medicine
来源：
Naunyn-Schmiedeberg's Archives of Pharmacology | 2023年 / 396卷
关键词：
Nephrotoxicity; Cisplatin; Gentamicin; ER stress; GRP78/BiP; PERK;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This study aimed to establish the relationship between two endoplasmic reticulum (ER) stress proteins, glucose-regulated protein 78 (GRP78/BiP) and PKR-like endoplasmic reticulum kinase (PERK), and oxidative stress markers in cisplatin (CIS)–induced and gentamicin (GEN)–induced nephrotoxicity.
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页码：789 / 801
页数：12
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