Vascular bioactivation of nitroglycerin: reaction mechanism revealed by crystal structure of aldehyde dehydrogenase-2

被引:0
|
作者
Barbara S Lang
Antonius CF Gorren
Gustav Oberdorfer
M Verena Wenzl
Cristina M Furdui
Leslie B Poole
Bernd Mayer
Karl Gruber
机构
[1] University of Graz,Department of Pharmacology and Toxicology, Institute of Pharmaceutical Sciences
[2] University of Graz,Institute of Molecular Biosciences
[3] Wake Forest School of Medicine,Department of Internal Medicine, Section of Molecular Medicine
[4] Wake Forest School of Medicine,Department of Biochemistry
关键词
Nitric Oxide; Hydrogen Bond; Aldehyde; Active Metabolite; Nitroglycerin;
D O I
10.1186/2050-6511-13-S1-A37
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