Single-cell epigenomic variability reveals functional cancer heterogeneity

被引：0
|
作者：
Ulrike M. Litzenburger
Jason D. Buenrostro
Beijing Wu
Ying Shen
Nathan C. Sheffield
Arwa Kathiria
William J. Greenleaf
Howard Y. Chang
机构：
[1] Stanford University School of Medicine,Center for Personal Dynamic Regulomes
[2] Stanford University School of Medicine,Department of Genetics
[3] Stanford University,Department of Applied Physics
[4] Broad Institute of MIT and Harvard,Harvard Society of Fellows
[5] Harvard University,undefined
来源：
Genome Biology | / 18卷
关键词：
Open chromatin; Gene expression noise; Cancer stem cells;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Single-cell transcriptomic profiling reveals the tumor heterogeneity of small-cell lung cancer
    Tian, Yanhua
    Li, Qingqing
    Yang, Zhenlin
    Zhang, Shu
    Xu, Jiachen
    Wang, Zhijie
    Bai, Hua
    Duan, Jianchun
    Zheng, Bo
    Li, Wen
    Cui, Yueli
    Wang, Xin
    Wan, Rui
    Fei, Kailun
    Zhong, Jia
    Gao, Shugeng
    He, Jie
    Gay, Carl M.
    Zhang, Jianjun
    Wang, Jie
    Tang, Fuchou
    SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022, 7 (01)
  • [22] Single-cell imaging of CAR T cell activity in vivo reveals extensive functional and anatomical heterogeneity
    Cazaux, Marine
    Grandjean, Capucine L.
    Lemaitre, Fabrice
    Garcia, Zacarias
    Beck, Richard J.
    Milo, Idan
    Postat, Jeremy
    Beltman, Joost B.
    Cheadle, Eleanor J.
    Bousso, Philippe
    JOURNAL OF EXPERIMENTAL MEDICINE, 2019, 216 (05): : 1038 - 1049
  • [23] Single-Cell Epigenomic Technology and Applications
    Yuan, Chongli
    Lin, Li
    Carneiro, Ana
    Xie, Junkai
    CHEMICAL ENGINEERING PROGRESS, 2018, 114 (09) : 63 - 70
  • [24] Single-cell Analysis Reveals Inter- and Intratumour Heterogeneity in Metastatic Breast Cancer
    Hamelin, Baptiste
    Obradovic, Milan M. S.
    Sethi, Atul
    Kloc, Michal
    Munst, Simone
    Beisel, Christian
    Eschbach, Katja
    Kohler, Hubertus
    Soysal, Savas
    Vetter, Marcus
    Weber, Walter P.
    Stadler, Michael B.
    Bentires-Alj, Mohamed
    JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 2023, 28 (01)
  • [25] Integration Analysis of Single-Cell Multi-Omics Reveals Prostate Cancer Heterogeneity
    Bian, Xiaojie
    Wang, Wenfeng
    Abudurexiti, Mierxiati
    Zhang, Xingming
    Ma, Weiwei
    Shi, Guohai
    Du, Leilei
    Xu, Midie
    Wang, Xin
    Tan, Cong
    Sun, Hui
    He, Xiadi
    Zhang, Chenyue
    Zhu, Yao
    Zhang, Min
    Ye, Dingwei
    Wang, Jianhua
    ADVANCED SCIENCE, 2024, 11 (18)
  • [26] Single-Cell Transcriptomics Reveals Heterogeneity and Drug Response of Human Colorectal Cancer Organoids
    Chen, Kai-Yuan
    Srinivasan, Tara
    Lin, Christopher
    Tung, Kuei-Ling
    Gao, Ziyang
    Hsu, David S.
    Lipkin, Steven M.
    Shen, Xiling
    2018 40TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), 2018, : 2378 - 2381
  • [27] Single-cell transcriptome analysis reveals heterogeneity and convergence of the tumor microenvironment in colorectal cancer
    Xie, Siyuan
    Cai, Yangke
    Chen, Delong
    Xiang, Yu
    Cai, Wen
    Mao, Jianshan
    Ye, Jun
    FRONTIERS IN IMMUNOLOGY, 2023, 13
  • [28] Single-cell Analysis Reveals Inter- and Intratumour Heterogeneity in Metastatic Breast Cancer
    Baptiste Hamelin
    Milan M. S. Obradović
    Atul Sethi
    Michal Kloc
    Simone Münst
    Christian Beisel
    Katja Eschbach
    Hubertus Kohler
    Savas Soysal
    Marcus Vetter
    Walter P. Weber
    Michael B. Stadler
    Mohamed Bentires-Alj
    Journal of Mammary Gland Biology and Neoplasia, 2023, 28
  • [29] Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages
    Ochocka, Natalia
    Segit, Pawel
    Walentynowicz, Kacper Adam
    Wojnicki, Kamil
    Cyranowski, Salwador
    Swatler, Julian
    Mieczkowski, Jakub
    Kaminska, Bozena
    NATURE COMMUNICATIONS, 2021, 12 (01)
  • [30] Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells
    Tan, David W. M.
    Jensen, Kim B.
    Trotter, Matthew W. B.
    Connelly, John T.
    Broad, Simon
    Watt, Fiona M.
    DEVELOPMENT, 2013, 140 (07): : 1433 - 1444
12345