Single-cell epigenomic variability reveals functional cancer heterogeneity

被引：0
|
作者：
Ulrike M. Litzenburger
Jason D. Buenrostro
Beijing Wu
Ying Shen
Nathan C. Sheffield
Arwa Kathiria
William J. Greenleaf
Howard Y. Chang
机构：
[1] Stanford University School of Medicine,Center for Personal Dynamic Regulomes
[2] Stanford University School of Medicine,Department of Genetics
[3] Stanford University,Department of Applied Physics
[4] Broad Institute of MIT and Harvard,Harvard Society of Fellows
[5] Harvard University,undefined
来源：
Genome Biology | / 18卷
关键词：
Open chromatin; Gene expression noise; Cancer stem cells;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Single-cell epigenomic variability reveals functional cancer heterogeneity
    Litzenburger, Ulrike M.
    Buenrostro, Jason D.
    Wu, Beijing
    Shen, Ying
    Sheffield, Nathan C.
    Kathiria, Arwa
    Greenleaf, William J.
    Chang, Howard Y.
    GENOME BIOLOGY, 2017, 18
  • [2] EpiCHAOS: a metric to quantify epigenomic heterogeneity in single-cell data
    Katherine Kelly
    Michael Scherer
    Martina Maria Braun
    Pavlo Lutsik
    Christoph Plass
    Genome Biology, 25 (1)
  • [3] Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity
    Xingqi Chen
    Ulrike M. Litzenburger
    Yuning Wei
    Alicia N. Schep
    Edward L. LaGory
    Hani Choudhry
    Amato J. Giaccia
    William J. Greenleaf
    Howard Y. Chang
    Nature Communications, 9
  • [4] Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity
    Chen, Xingqi
    Litzenburger, Ulrike M.
    Wei, Yuning
    Schep, Alicia N.
    LaGory, Edward L.
    Choudhry, Hani
    Giaccia, Amato J.
    Greenleaf, William J.
    Chang, Howard Y.
    NATURE COMMUNICATIONS, 2018, 9
  • [5] Single-cell analysis reveals cancer stem cell heterogeneity in hepatocellular carcinoma
    Zheng, Hongping
    Pomyen, Yotsawat
    Hernandez, Maria Olga
    Li, Caiyi
    Livak, Ferenc
    Tang, Wei
    Dang, Hien
    Greten, Tim F.
    Davis, Jeremy L.
    Zhao, Yongmei
    Mehta, Monika
    Levin, Yelena
    Shetty, Jyoti
    Tran, Bao
    Budhu, Anuradha
    Wang, Xin Wei
    HEPATOLOGY, 2018, 68 (01) : 127 - 140
  • [6] Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation
    Tischner, Denise
    Grimm, Myriam
    Kaur, Harmandeep
    Staudenraus, Daniel
    Carvalho, Jorge
    Looso, Mario
    Guenther, Stefan
    Wanke, Florian
    Moos, Sonja
    Siller, Nelly
    Breuer, Johanna
    Schwab, Nicholas
    Zipp, Frauke
    Waisman, Ari
    Kurschus, Florian C.
    Offermanns, Stefan
    Wettschureck, Nina
    JCI INSIGHT, 2017, 2 (15)
  • [7] Single-cell profiling reveals tumor heterogeneity and cell lineage diversity in gastric cancer
    Sun, Chuwen
    GUT, 2023, 72 (SUPPL_1) : A76 - A76
  • [8] Single-cell transcriptome sequencing reveals heterogeneity of gastric cancer: progress and prospects
    Deng, Gaohua
    Zhang, Xu
    Chen, Yonglan
    Liang, Sicheng
    Liu, Sha
    Yu, Zehui
    Lu, Muhan
    FRONTIERS IN ONCOLOGY, 2023, 13
  • [9] Single-cell transcriptomics reveals clonal diversity and tumor heterogeneity in gastric cancer
    Koh, Vivien
    Kalpana, Ramnarayanan
    Li, Huipeng
    Nandi, Tannistha
    Tan, Angie
    Prabhakar, Shyam
    Chen, Jinmiao
    Chan, Shing Leng
    Shabbir, Asim
    So, Jimmy
    Tan, Patrick
    Yong, Wei Peng
    CANCER SCIENCE, 2018, 109 : 609 - 609
  • [10] Single-cell transcriptomics reveals cellular heterogeneity and molecular stratification of cervical cancer
    Chunbo Li
    Hao Wu
    Luopei Guo
    Danyang Liu
    Shimin Yang
    Shengli Li
    Keqin Hua
    Communications Biology, 5
12345