Oxidative stress, protein damage and repair in bacteria

被引:0
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作者
Benjamin Ezraty
Alexandra Gennaris
Frédéric Barras
Jean-François Collet
机构
[1] Aix-Marseille Université,
[2] CNRS,undefined
[3] Laboratoire de Chimie Bactérienne,undefined
[4] UMR 7283,undefined
[5] Institut de Microbiologie de la Méditerranée,undefined
[6] WELBIO,undefined
[7] de Duve Institute,undefined
[8] Université catholique de Louvain,undefined
[9] Brussels Center for Redox Biology,undefined
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摘要
Bacterial proteins can be damaged by oxidants that are present in the environment.Cys and Met residues are easily oxidized.Bacterial cells have a range of proteins that repair oxidized proteins.Thioredoxins (Trxs) and glutaredoxins (Grxs) repair oxidized cysteine residues.Methionine sulfoxide reductases (Msrs) repair oxidized methionine residues.Antioxidant defences are present in the bacterial cytoplasm and in extracytoplasmic compartments.
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页码:385 / 396
页数:11
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