The use of tacrolimus for recurrent lupus enteritis: A case report

被引：10
|
作者：
Shirai T. [1 ]
Hirabayashi Y. [1 ]
Watanabe R. [1 ]
Tajima Y. [1 ]
Fujii H. [1 ]
Takasawa N. [1 ]
Ishii T. [1 ]
Harigae H. [1 ]
机构：
[1] Department of Rheumatology and Hematology, Tohoku University Graduate School of Medicine, Seiryo-cho, Aoba-ku, Sendai
来源：
Journal of Medical Case Reports | / 4卷 / 1期
关键词：
Systemic Lupus Erythematosus; Tacrolimus; Systemic Lupus Erythematosus Disease Activity Index; Capillary Leak Syndrome; Eosinophilic Gastroenteritis;
D O I：
10.1186/1752-1947-4-150
中图分类号：
学科分类号：
摘要：
Introduction. Patients with lupus enteritis sometimes experience recurrence. In such cases, the addition of cyclophosphamide to the treatment regimen is recommended. However, an appropriate treatment has not been established in cases where cyclophosphamide failed to prevent the disease. Case presentation. An 18-year-old Japanese woman was admitted for a recurrence of lupus enteritis. One year before admission she was treated for lupus enteritis with high-dose corticosteroid together with intravenous cyclophosphamide pulse therapy. Upon admission, she was administered again with high-dose corticosteroid and her abdominal pain rapidly subsided. Tacrolimus was later used as an immunosuppressive agent and a complete remission has been maintained. Conclusion. Tacrolimus can be a useful agent for recurrent lupus enteritis that is resistant to conventional therapy. © 2010 Shirai et al; licensee BioMed Central Ltd.
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