Targeted next-generation sequencing reveals high frequency of mutations in epigenetic regulators across treatment-naïve patient melanomas

被引：0
|
作者：
Jonathan J. Lee
Lynette M. Sholl
Neal I. Lindeman
Scott R. Granter
Alvaro C. Laga
Priyanka Shivdasani
Gary Chin
Jason J. Luke
Patrick A. Ott
F. Stephen Hodi
Martin C. Mihm
Jennifer Y. Lin
Andrew E. Werchniak
Harley A. Haynes
Nancy Bailey
Robert Liu
George F. Murphy
Christine G. Lian
机构：
[1] Brigham and Women’s Hospital,Department of Pathology
[2] Harvard Medical School,undefined
[3] Melanoma Center,undefined
[4] Dana–Farber Cancer Institute,undefined
[5] Harvard Medical School,undefined
来源：
Clinical Epigenetics | 2015年 / 7卷
关键词：
Melanoma; Next-generation sequencing (NGS); Epigenetics; (MDS1 and EV1 complex locus); Ten-eleven translocation (TET); Isocitrate dehydrogenase 2 (IDH2); 5-hydroxymethylcytosine; DNA demethylation;
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