Exacerbation of Chronic Obstructive Pulmonary Disease

被引:0
|
作者
Xianghui Zhou
Qingling Li
Xincan Zhou
机构
[1] The First Xuzhou People’s Hospital,Department of Respiratory Medicine
来源
关键词
COPD; Exacerbation; Virus; Bacteria; Innate immunity; Inflammation; Review;
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学科分类号
摘要
Chronic obstructive pulmonary disease (COPD) is a disease with high prevalence and substantial associated economical burden. A significant determinant of quality of life, long-term survival, and health care costs is an acute exacerbation of COPD. Acute exacerbations are provoked by respiratory viruses, altered airway microbiome, and environmental factors. The current treatment options are limited. In order to develop specific therapeutic measures, it is important to understand how acute exacerbations evolve. This review focuses on pathophysiology of stable and exacerbated COPD.
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页码:349 / 355
页数:6
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