Exacerbation phenotyping in chronic obstructive pulmonary disease

被引:32
|
作者
MacDonald, Martin [1 ]
Korman, Tony [1 ]
King, Paul [1 ]
Hamza, Kais [1 ]
Bardin, Philip [1 ]
机构
[1] Monash Med Ctr, Melbourne, Vic, Australia
关键词
clinical respiratory medicine; chronic obstructive pulmonary disease; emphysema; infection and inflammation; viral infection;
D O I
10.1111/resp.12197
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are crucial events but causes remain poorly defined. A method to clinically phenotype' AECOPD have been proposed, and 52 hospitalized chronic obstructive pulmonary disease exacerbations according to underlying aetiology have now been prospectively phenotyped. Multiple exacerbation phenotypes were identified. A subpopulation coinfected with virus and bacteria had a significantly longer length of hospital stay, and this pilot study indicates that exacerbation phenotyping may be advantageous.
引用
收藏
页码:1280 / 1281
页数:2
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