Pseudomonas aeruginosa: Characteristics of the biofilm process

In this review, we define the biofilm process as a type of intercellular bacterial communication. We present up-to-date data on the structure of the Pseudomonas aeruginosa biofilm matrix and genetic mechanisms regulating its formation, discuss processes involved in active or passive rejection of the biofilm bacteria that promotes their spreading and attaching to new surfaces, and stress the complexity and chain character of reactions associated with biofilm formation.