Phase IB study of sorafenib in combination with gemcitabine and cisplatin in patients with refractory solid tumors

被引:0
|
作者
B. Schultheis
G. Kummer
M. Zeth
E. Brendel
C. Xia
M. Kornacker
D. Strumberg
机构
[1] University of Bochum (Marienhospital Herne),Department of Haematology and Medical Oncology
[2] Bayer HealthCare Pharmaceuticals,undefined
[3] Bayer HealthCare Pharmaceuticals,undefined
[4] Bayer HealthCare Pharmaceuticals,undefined
来源
关键词
Phase I; Sorafenib; Gemcitabine; Cisplatin; Multiple kinase inhibitor; Pharmacokinetics;
D O I
暂无
中图分类号
学科分类号
摘要
引用
下载
收藏
页码:333 / 339
页数:6
相关论文
共 50 条
  • [1] Phase IB study of sorafenib in combination with gemcitabine and cisplatin in patients with refractory solid tumors
    Schultheis, B.
    Kummer, G.
    Zeth, M.
    Brendel, E.
    Xia, C.
    Kornacker, M.
    Strumberg, D.
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2012, 69 (02) : 333 - 339
  • [2] A PHASE IB PHARMACOLOGICAL STUDY OF SORAFENIB IN COMBINATION WITH GEMCITABINE/CISPLATIN IN PATIENTS WITH REFRACTORY SOLID TUMORS INCLUDING NON-SMALL CELL LUNG CANCER
    Schultheis, B.
    Kummer, G.
    Zeth, M.
    Brendel, E.
    Kornacker, M.
    Strumberg, D.
    ANNALS OF ONCOLOGY, 2010, 21 : 155 - 155
  • [3] Phase Ib study of dovitinib in combination with gemcitabine plus cisplatin or gemcitabine plus carboplatin in patients with advanced solid tumors
    Galsky, Matthew D.
    Posner, Marshall
    Holcombe, Randall F.
    Lee, Karen M.
    Misiukiewicz, Krzysztof
    Tsao, Che-Kai
    Godbold, James
    Soto, Rothschild
    Gimpel-Tetra, Kiev
    Lowe, Nancy
    Oh, William K.
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2014, 74 (03) : 465 - 471
  • [4] Phase Ib study of dovitinib in combination with gemcitabine plus cisplatin or gemcitabine plus carboplatin in patients with advanced solid tumors
    Matthew D. Galsky
    Marshall Posner
    Randall F. Holcombe
    Karen M. Lee
    Krzysztof Misiukiewicz
    Che-Kai Tsao
    James Godbold
    Rothschild Soto
    Kiev Gimpel-Tetra
    Nancy Lowe
    William K. Oh
    Cancer Chemotherapy and Pharmacology, 2014, 74 : 465 - 471
  • [5] Phase I dose-escalation study of plitidepsin in combination with sorafenib or gemcitabine in patients with refractory solid tumors or lymphomas
    Aspeslagh, Sandrine
    Stein, Mark
    Bahleda, Rastilav
    Hollebecque, Antoine
    Salles, Gilles
    Gyan, Emmanuel
    Fudio, Salvador
    Extremera, Sonia
    Alfaro, Vicente
    Soto-Matos, Arturo
    Soria, Jean-Charles
    ANTI-CANCER DRUGS, 2017, 28 (03) : 341 - 349
  • [6] Phase Ib study of plitidepsin (APL) with gemcitabine (GEM) in refractory solid tumors and lymphoma patients
    Stein, Mark N.
    Ribrag, Vincent
    Gomez-Roca, Carlos Alberto
    Salles, Gilles A.
    Carella, Angelo Michele
    Gyan, Emmanuel
    Szyldergemajn, Sergio A.
    Kahatt, Carmen Maria
    Luque, Manuel
    Extremera, Sonia
    De Miguel, Bernardo
    Fernandez-Garcia, Eva
    Soria, Jean-Charles
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [7] Phase Ib study of adavosertib in combination with olaparib in patients with refractory solid tumors: Dose escalation
    Hamilton, Erika
    Falchook, Gerald S.
    Wang, Judy S.
    Fu, Siqing
    Oza, Amit
    Karen, So
    Imedio, Esteban Rodrigo
    Kumar, Sanjeev
    Ottesen, Lone
    Mugundu, Ganesh M.
    Chmielecki, Juliann
    Jones, Suzanne
    Spigel, David R.
    Li, Bob T.
    CANCER RESEARCH, 2019, 79 (13)
  • [8] A Phase I Combination Study of Olaparib with Cisplatin and Gemcitabine in Adults with Solid Tumors
    Rajan, Arun
    Carter, Corey A.
    Kelly, Ronan J.
    Gutierrez, Martin
    Kummar, Shivaani
    Szabo, Eva
    Yancey, Mary Ann
    Ji, Jiuping
    Mannargudi, Baskar
    Woo, Sukyung
    Spencer, Shawn
    Figg, William Douglas
    Giaccone, Giuseppe
    CLINICAL CANCER RESEARCH, 2012, 18 (08) : 2344 - 2351
  • [9] Phase Ib study of NGR-hTNF, a selective vascular targeting agent (VTA), in combination with cisplatin in patients with refractory solid tumors
    Citterio, G.
    De Braud, F. G.
    Gregorc, V.
    De Pas, T. M.
    Scalamogna, R.
    Boselli, S.
    Giovannini, M.
    Caligaris-Cappio, F.
    Lambiase, A.
    Bordignon, C.
    JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (15)
  • [10] Pharmacokinetic schedule finding study of the combination of gemcitabine and cisplatin in patients with solid tumors
    van Moorsel, CJA
    Kroep, JR
    Pinedo, HM
    Veerman, G
    Voorn, DA
    Postmus, PE
    Vermorken, JB
    van Groeningen, CJ
    van der Vijgh, WJF
    Peters, GJ
    ANNALS OF ONCOLOGY, 1999, 10 (04) : 441 - 448