Bacterial proteases: targets for diagnostics and therapy

被引：0
|
作者：
W. E. Kaman
J. P. Hays
H. P. Endtz
F. J. Bikker
机构：
[1] Erasmus MC,Department of Medical Microbiology and Infectious Diseases
[2] University of Amsterdam and VU University Amsterdam,Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam
来源：
European Journal of Clinical Microbiology & Infectious Diseases | 2014年 / 33卷
关键词：
Disseminate Intravascular Coagulation; Peptide Substrate; Bacterial Virulence; Lethal Factor; Bacterial Protease;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Proteases are essential for the proliferation and growth of bacteria, and are also known to contribute to bacterial virulence. This makes them interesting candidates as diagnostic and therapeutic targets for infectious diseases. In this review, the authors discuss the most recent developments and potential applications for bacterial proteases in the diagnosis and treatment of bacterial infections. Current and future bacterial protease targets are described and their limitations outlined.
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页码：1081 / 1087
页数：6
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