Secondary donor-derived humanized CD19-modified CAR-T cells induce remission in relapsed/refractory mixed phenotype acute leukemia after allogeneic hematopoietic stem cell transplantation: a case report

被引：0
|
作者：
Meng-Yun Li
Zhi-Hong Lin
Ming-Ming Hu
Li-Qing Kang
Xiao-xia Wu
Qi-wei Chen
Xin Kong
Jian Zhang
Hui-Ying Qiu
De-Pei Wu
机构：
[1] The First Affiliated Hospital of Soochow University,Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, Collaborative Innovation Center of Hematology
[2] Institute of Blood and Marrow Transplantation,Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development
[3] Soochow University,undefined
[4] Suzhou Yongding Hospital,undefined
[5] School of Chemistry and Molecular Engineering,undefined
[6] East China Normal University,undefined
[7] Shanghai Unicar-Therapy Bio-medicine Technology Co.,undefined
[8] Ltd,undefined
来源：
Biomarker Research | / 8卷
关键词：
CD19; Chimeric antigen receptor T cells; Donor-derived; Humanized; Mixed phenotype acute leukemia;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Donor-derived CD19 CAR-T Cells versus Chemotherapy Plus Donor Lymphocyte Infusion for Treatment of Recurrent CD19-positive B-ALL After Allogeneic Hematopoietic Stem Cell Transplantation
    Xu Tan
    Xiao-qi Wang
    Cheng Zhang
    Xian-lan Zhao
    Han Yao
    Guo Chen
    Ying-ying Ma
    Qin Wen
    Lei Gao
    Li Gao
    Pei-yan Kong
    Yan Shen
    Xi Zhang
    Shi-feng Lou
    Current Medical Science, 2023, 43 : 733 - 740
  • [32] Allogeneic Hematopoietic Stem Cell Transplantation with Conditioning Including Donor Humanized CAR-T Cells for Refractory/Relapsed B-Cell Non-Hodgkin Lymphoma and Multiple Myeloma
    Yang, Fan
    Shi, Hui
    Lei, Yang
    Li, Ruiting
    Xu, Teng
    Deng, Biping
    Wu, Tong
    Ke, Xiaoyan
    Hu, Kai
    BLOOD, 2021, 138
  • [33] Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation
    Kochenderfer, James N.
    Dudley, Mark E.
    Carpenter, Robert O.
    Kassim, Sadik H.
    Rose, Jeremy J.
    Telford, William G.
    Hakim, Frances T.
    Halverson, David C.
    Fowler, Daniel H.
    Hardy, Nancy M.
    Mato, Anthony R.
    Hickstein, Dennis D.
    Gea-Banacloche, Juan C.
    Pavletic, Steven Z.
    Sportes, Claude
    Maric, Irina
    Feldman, Steven A.
    Hansen, Brenna G.
    Wilder, Jennifer S.
    Blacklock-Schuver, Bazetta
    Jena, Bipulendu
    Bishop, Michael R.
    Gress, Ronald E.
    Rosenberg, Steven A.
    BLOOD, 2013, 122 (25) : 4129 - 4139
  • [34] Donor-derived anti-CD19 CAR T cells compared with donor lymphocyte infusion for recurrent B-ALL after allogeneic hematopoietic stem cell transplantation
    Jingsheng Hua
    Jian Zhang
    Xinyou zhang
    Xiaoxia Wu
    Lili Zhou
    Xiebing Bao
    Yue Han
    Miao Miao
    Caixia Li
    Chengcheng Fu
    Suning Chen
    Xiaowen Tang
    Depei Wu
    Huiying Qiu
    Bone Marrow Transplantation, 2021, 56 : 1056 - 1064
  • [35] Donor-derived anti-CD19 CAR T cells compared with donor lymphocyte infusion for recurrent B-ALL after allogeneic hematopoietic stem cell transplantation
    Hua, Jingsheng
    Zhang, Jian
    Zhang, Xinyou
    Wu, Xiaoxia
    Zhou, Lili
    Bao, Xiebing
    Han, Yue
    Miao, Miao
    Li, Caixia
    Fu, Chengcheng
    Chen, Suning
    Tang, Xiaowen
    Wu, Depei
    Qiu, Huiying
    BONE MARROW TRANSPLANTATION, 2021, 56 (05) : 1056 - 1064
  • [36] Prophylactic donor-derived CD19 CAR-T cell infusion for preventing relapse in high-risk B-ALL after allogeneic hematopoietic stem cell transplantation
    Lu, Wenyi
    Lyu, Hairong
    Xiao, Xia
    Bai, Xue
    Zhang, Meng
    Wang, Jiaxi
    Pu, Yedi
    Meng, Juanxia
    Zhang, Xiaomei
    Zhu, Haibo
    Yuan, Ting
    Wang, Bing
    Jin, Xin
    Cao, Xinping
    Wang, Zhao
    Xie, Tianle
    Meng, Haotian
    Stepanov, Alexey V.
    Gabibov, Alexander G.
    An, Yuxin
    Sun, Rui
    Zhang, Yu
    Maschan, Mikhail A.
    Zhu, Zunmin
    Zhang, Hongkai
    Zhao, Mingfeng
    LEUKEMIA, 2024, 38 (06) : 1419 - 1422
  • [37] Case report: Preventive infusion of donor-derived CD7 chimeric antigen receptor T cells after allogeneic hematopoietic stem cell transplantation
    Jiang, Ying
    Feng, Dan
    Zhu, Jun
    Wei, Daolin
    Zhao, Chuxian
    Liu, Huixia
    Shao, Shan
    Wang, Chun
    FRONTIERS IN IMMUNOLOGY, 2024, 15
  • [38] CD38-directed CAR-T cell therapy: a novel immunotherapy strategy for relapsed acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation
    Qingya Cui
    Chongsheng Qian
    Nan Xu
    Liqing Kang
    Haiping Dai
    Wei Cui
    Baoquan Song
    Jia Yin
    Zheng Li
    Xiaming Zhu
    Changju Qu
    Tianhui Liu
    Wenhong Shen
    Mingqing Zhu
    Lei Yu
    Depei Wu
    Xiaowen Tang
    Journal of Hematology & Oncology, 14
  • [39] CD38-Directed CAR-T Cell Therapy: A Novel Immunotherapy Strategy for Relapsed Acute Myeloid Leukemia after Allogeneic Hematopoietic Stem Cell Transplantation
    Tang, Xiaowen
    Wu, Depei
    Cui, Qingya
    Qian, Chongsheng
    Xu, Nan
    Kang, Liqing
    Dai, Haiping
    Song, Baoquan
    Cui, Wei
    Yin, Jia
    Li, Zheng
    Yu, Lei
    BLOOD, 2020, 136
  • [40] CD38-directed CAR-T cell therapy: a novel immunotherapy strategy for relapsed acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation
    Cui, Qingya
    Qian, Chongsheng
    Xu, Nan
    Kang, Liqing
    Dai, Haiping
    Cui, Wei
    Song, Baoquan
    Yin, Jia
    Li, Zheng
    Zhu, Xiaming
    Qu, Changju
    Liu, Tianhui
    Shen, Wenhong
    Zhu, Mingqing
    Yu, Lei
    Wu, Depei
    Tang, Xiaowen
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2021, 14 (01)
12345