Two New Polyhydroxylated Sterol Derivatives from the Sponge Topsentia sp. Collected from the South China Sea

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作者
Min Chen
Xu-Dong Wu
Jun-Di Hao
Chang-Yun Wang
机构
[1] Ocean University of China,Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy
[2] Yangzhou University,Marine Science & Technology Institute, College of Environmental Science & Engineering
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sponge; sp.; polyhydroxylated steroid; topsensterol;
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摘要
Further chemical investigation of the marine sponge Topsentio sp. collected from the South China Sea led to the isolation of two new polyhydroxylated sterol derivatives, topsensterol D (1) and 4β-hydroxyhalistanol (2). Their structures were elucidated by detailed analysis of the spectroscopic data including 1D and 2D NMR spectral data. Their cytotoxic activities were evaluated.
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页码:301 / 304
页数:3
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