4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, a Nicotine-derived Carcinogenic Nitrosaminoketone (NNK): Three-dimensional Structure

被引：0

作者：

Amy K. Katz

H. L. Carrell

Carol E. Afshar

Jenny P. Glusker

Dhimant Desai

Shantu Amin

机构：

[1] The Institute for Cancer Research,Fox Chase Cancer Center

[2] American Health Foundation,undefined

来源：

Structural Chemistry | 1999年 / 10卷

关键词：

Nicotine-derived nitrosaminoketone; nitrosamine; crystal structure; molecular dimensions;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The three-dimensional structure of the carcinogenic nicotine-derived nitrosaminoketone, 4-(methyl-nitrosamino)-l-(3-pyridyl)-l-butanone, has been determined by X-ray crystallographic techniques. The molecule is essentially planar except for the methylnitrosamine group which is oriented at a dihedral angle of 68.7° to the pyridine ring. Molecules pack by way of —H⋯O interactions that involve the —NNO group.

引用

页码：439 / 443

页数：4

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