Lymphocyte senescence in COPD is associated with decreased histone deacetylase 2 expression by pro-inflammatory lymphocytes

被引:0
|
作者
Greg Hodge
Hubertus Jersmann
Hai B. Tran
Eugene Roscioli
Mark Holmes
Paul N. Reynolds
Sandra Hodge
机构
[1] Royal Adelaide Hospital,Lung Research, Hanson Institute and Department of Thoracic Medicine
[2] University of Adelaide,Department of Medicine
来源
关键词
Lymphocyte senescence; COPD; HDAC2; CD28nullCD8+ T and NKT-like cells; IFNγ and TNFα;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] Decreased heart rate is associated with carbamate-induced activation of pro-inflammatory serum proteins
    Mack, CM
    Becker, PB
    Gordon, CJ
    FASEB JOURNAL, 2006, 20 (05): : A1103 - A1103
  • [42] BOS IS ASSOCIATED WITH DECREASED SIRT1 IN PERIPHERAL BLOOD PRO-INFLAMMATORY T AND NKT-LIKE LYMPHOCYTES FOLLOWING LUNG TRANSPLANT
    Hodge, G.
    Hodge, S.
    Holmes-Liew, C.
    Reynolds, P.
    Holmes, M.
    RESPIROLOGY, 2019, 24 : 94 - 94
  • [43] The drug efflux pump Pgp1 in pro-inflammatory lymphocytes is a target for novel treatment strategies in COPD
    Greg Hodge
    Mark Holmes
    Hubertus Jersmann
    Paul N Reynolds
    Sandra Hodge
    Respiratory Research, 14
  • [44] Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema
    Sundar, Isaac K.
    Rashid, Kahkashan
    Gerloff, Janice
    Rangel-Moreno, Javier
    Li, Dongmei
    Rahman, Irfan
    FASEB JOURNAL, 2018, 32 (09): : 4955 - 4971
  • [45] Pan-histone deacetylase inhibitors regulate signaling pathways involved in proliferative and pro-inflammatory mechanisms in H9c2 cells
    Majumdar, Gipsy
    Adris, Piyatilake
    Bhargava, Neha
    Chen, Hao
    Raghow, Rajendra
    BMC GENOMICS, 2012, 13
  • [46] Pan-histone deacetylase inhibitors regulate signaling pathways involved in proliferative and pro-inflammatory mechanisms in H9c2 cells
    Gipsy Majumdar
    Piyatilake Adris
    Neha Bhargava
    Hao Chen
    Rajendra Raghow
    BMC Genomics, 13
  • [47] BLTR1 Is Decreased in Steroid Resistant Pro-Inflammatory CD28nullCD8+T Lymphocytes in Patients with COPD-The Spillover Hypothesis Explained?
    Hodge, Greg
    Jersmann, Hubertus
    Holmes, Mark
    Asare, Patrick
    Roscioli, Eugene
    Reynolds, Paul N.
    Hodge, Sandra
    BIOLOGY-BASEL, 2023, 12 (09):
  • [48] Decreased pro-inflammatory cytokines and increased CCR7 expression on T-lymphocyte subsets are predictive of response to extracorporeal photopheresis in patients with GvHD
    Aoki, Masayuki
    Marin-Esteban, Viviana
    Weigl, Roman
    Charron, Dominique
    Greinix, Hildegard
    Moins-Teisserenc, Helene
    Mooney, Nuala
    BRITISH JOURNAL OF HAEMATOLOGY, 2011, 154 (03) : 409 - 413
  • [49] Decreased low-density lipoprotein receptor-related protein 1 expression in pro-inflammatory monocytes is associated with subclinical atherosclerosis
    Albertini, Ricardo A.
    Nicolas, Juan C.
    Dato, Virginia Actis
    Ferrer, Dario G.
    Tinti, Maria E.
    Capra, Raul H.
    Chiabrando, Gustavo A.
    FRONTIERS IN CARDIOVASCULAR MEDICINE, 2022, 9
  • [50] COPD IS ASSOCIATED WITH INCREASED PGP-1 EXPRESSION IN PRO-INFLAMMATORY PERIPHERAL BLOOD T, NK AND NKT-LIKE CELLS
    Hodge, G.
    Jersmann, H.
    Ahern, J.
    Holmes, M.
    Reynolds, P. N.
    Hodge, S.
    RESPIROLOGY, 2013, 18 : 32 - 32