Development, maintenance and disruption of the blood-brain barrier

被引:0
|
作者
Birgit Obermeier
Richard Daneman
Richard M Ransohoff
机构
[1] Neuroinflammation Research Center,Department of Neuroscience
[2] Lerner Research Institute,Department of Anatomy
[3] Cleveland Clinic,undefined
[4] University of California,undefined
来源
Nature Medicine | 2013年 / 19卷
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摘要
The blood-brain barrier (BBB) has a key role in maintaining brain homeostasis and, thus, brain function. This Review outlines recent advances in understanding the development and maintenance of the BBB and the contribution of BBB disruption to various neurological diseases. It also discusses how such insights might be used to design new therapeutic strategies for BBB repair.
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页码:1584 / 1596
页数:12
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