GRK2 blockade with βARKct is essential for cardiac β2-adrenergic receptor signaling towards increased contractility

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作者
Norma C Salazar
Ximena Vallejos
Ashley Siryk
Giuseppe Rengo
Alessandro Cannavo
Daniela Liccardo
Claudio De Lucia
Erhe Gao
Dario Leosco
Walter J Koch
Anastasios Lymperopoulos
机构
[1] Nova Southeastern University College of Pharmacy,Department of Pharmaceutical Sciences, Laboratory for the Study of Neurohormonal Control of the Circulation
[2] University “Federico II“,Division of Cardiology, Department of Internal Medicine, Cardiovascular Sciences and Immunology
[3] Temple University,Center for Translational Medicine
关键词
Cardiac β; –adrenergic receptor; Pro-contractile signaling; Post-myocardial infarction survival; GRK2 inhibition; GRK5;
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