Patched-2 functions to limit Patched-1 deficient skin cancer growth

被引：0
|
作者：
Veronique L. Veenstra
Ilse Dingjan
Cynthia Waasdorp
Helene Damhofer
Allard C. van der Wal
Hanneke W. van Laarhoven
Jan Paul Medema
Maarten F. Bijlsma
机构：
[1] Laboratory for Experimental Oncology and Radiobiology,Tumor Immunology Lab
[2] Center for Experimental and Molecular Medicine,undefined
[3] Cancer Center Amsterdam and Academic Medical Center,undefined
[4] Oncode Institute,undefined
[5] Academic Medical Center,undefined
[6] Radboud Institute for Molecular Life Sciences,undefined
[7] Biotech Research & Innovation Centre,undefined
[8] Department of Pathology,undefined
[9] Academic Medical Center,undefined
[10] Department of Medical Oncology,undefined
[11] Cancer Center Amsterdam and Academic Medical Center,undefined
来源：
Cellular Oncology | 2018年 / 41卷
关键词：
Basal cell carcinoma; Hedgehog signaling; Patched; Smoothened;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：427 / 437
页数：10
相关论文
共 50 条
  • [31] Patched1 and Patched2 inhibit Smoothened non-cell autonomously
    Roberts, Brock
    Casillas, Catalina
    Alfaro, Astrid C.
    Jagers, Carina
    Roelink, Henk
    ELIFE, 2016, 5
  • [32] Mutations in PATCHED-1, the receptor for SONIC HEDGEHOG, are associated with holoprosencephaly (vol 110, pg 297, 2002)
    Ming, JE
    Kaupas, ME
    Roessler, E
    Brunner, HG
    Golabi, M
    Tekin, M
    Stratton, RF
    Sujansky, E
    Bale, SJ
    Muenke, M
    HUMAN GENETICS, 2002, 111 (4-5) : 464 - 464
  • [33] Patched-1和Gli-1在银屑病皮损中的表达
    刘瑛
    李承新
    陈凌
    刘玉峰
    中华皮肤科杂志, 2006, (09) : 506 - 508
  • [34] RETINOIC ACID-INDUCED PLACENTAL VASCULAR HYPOPLASIA WITH PATCHED-1 UP-REGULATION IN RATS
    Kajiwara, Kazuhiro
    Oishi, Yoshie
    Sato, Taisuke
    Matsuoka, Tomona
    Yamamura, Michihiro
    Udagawa, Haruhiko
    Inoue, Momoko
    Ito, Yuki
    Kamide, Taizan
    Wada, Seiji
    Akutsu, Hidenori
    Samura, Osamu
    Sago, Haruhiko
    Umezawa, Akihiro
    Okamoto, Aikou
    PLACENTA, 2018, 69 : E5 - E6
  • [35] Developmental genes and cancer: Role of patched in basal cell carcinoma of the skin
    Gailani, MR
    Bale, AE
    JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1997, 89 (15): : 1103 - 1109
  • [36] Spectrum of mutations in the tumor-suppressor gene, patched-1, in patients with nevoid basal cell carcinoma syndrome
    Miyashita, T.
    NEURO-ONCOLOGY, 2007, 9 (02) : 183 - 183
  • [37] Molecular modelling of human PATCHED-1 may incentivize development of novel therapies for advanced basal cell carcinoma
    Hernandez, J.
    Kim, M.
    Kulkarni, V.
    Goode, M. A.
    Graham, S.
    Lane, M. P.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2024, 144 (08) : S144 - S144
  • [38] Multipotent CD15+ Cancer Stem Cells in Patched-1-Deficient Mouse Medulloblastoma
    Ward, Ryan J.
    Lee, Lilian
    Graham, Kevin
    Satkunendran, Thevagi
    Yoshikawa, Koichi
    Ling, Erick
    Harper, Lauren
    Austin, Ryan
    Nieuwenhuis, Erica
    Clarke, Ian D.
    Hui, Chi-chung
    Dirks, Peter B.
    CANCER RESEARCH, 2009, 69 (11) : 4682 - 4690
  • [39] The cell adhesion molecule CHL1 interacts with patched-1 to regulate apoptosis during postnatal cerebellar development
    Katic, Jelena
    Loers, Gabriele
    Tosic, Jelena
    Schachner, Melitta
    Kleene, Ralf
    JOURNAL OF CELL SCIENCE, 2017, 130 (15) : 2606 - 2619
  • [40] Patched1 functions as a gatekeeper by promoting cell cycle progression
    Adolphe, C
    Hetherington, R
    Ellis, T
    Wainwright, B
    CANCER RESEARCH, 2006, 66 (04) : 2081 - 2088
12345