Targeting the myeloid checkpoint receptor SIRPα potentiates innate and adaptive immune responses to promote anti-tumor activity

被引:0
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作者
Tracy C. Kuo
Amy Chen
Ons Harrabi
Jonathan T. Sockolosky
Anli Zhang
Emma Sangalang
Laura V. Doyle
Steven E. Kauder
Danielle Fontaine
Sangeetha Bollini
Bora Han
Yang-Xin Fu
Janet Sim
Jaume Pons
Hong I. Wan
机构
[1] ALX Oncology,Department of Pathology
[2] University of Texas Southwestern Medical Center,undefined
[3] Tallac Therapeutics,undefined
[4] Genentech,undefined
[5] Coherus BioSciences,undefined
[6] ProLynx Inc.,undefined
关键词
SIRPα; CD47; Macrophage; Phagocytosis; Immunotherapy; Innate immune checkpoint; Adaptive immunity;
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