HIF-1α links β-adrenoceptor agonists and pancreatic cancer cells under normoxic condition

被引：0
|
作者：
Heng-tong Hu
Qing-yong Ma
Dong Zhang
Su-gang Shen
Liang Han
Ya-dong Ma
Ruo-fei Li
Ke-ping Xie
机构：
[1] The First Affiliated Hospital of Medical College,Department of Hepatobiliary Surgery
[2] Xi'an Jiaotong University,Department of Urinary Surgery
[3] The Second Affiliated Hospital of Medical College,Department of Osteological Surgery
[4] Xi'an Jiaotong University,Department of Cancer Biology
[5] The Second Affiliated Hospital of Medical College,undefined
[6] Xi'an Jiaotong University,undefined
[7] University of Texas MD Anderson Cancer Center,undefined
来源：
Acta Pharmacologica Sinica | 2010年 / 31卷
关键词：
β-adrenergic receptor; epidermal growth factor receptor; hypoxia-inducible factor-1α; protein kinase A; ERK1/2; Akt; hypothalamic-pituitary-adrenal axis; pancreatic cancer;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：102 / 110
页数：8
相关论文
共 50 条
  • [41] Hypoxia, HIF-1, and cancer
    Semenza, G. L.
    CLINICAL & EXPERIMENTAL METASTASIS, 2008, 25 : 20 - 20
  • [42] Digoxin, HIF-1, and cancer
    Lopez-Lazaro, Miguel
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (09) : E26 - E26
  • [43] Gemcitabine Resistance is Associated with Epithelial-Mesenchymal Transition and Induction of HIF-1α in Pancreatic Cancer Cells
    Wang, Rui
    Cheng, Long
    Xia, Jun
    Wang, Zishu
    Wu, Qiong
    Wang, Zhiwei
    CURRENT CANCER DRUG TARGETS, 2014, 14 (04) : 407 - 417
  • [44] CD133 Modulate HIF-1 Expression under Hypoxia in EMT Phenotype Pancreatic Cancer Stem-Like Cells
    Maeda, Koki
    Ding, Qiang
    Yoshimitsu, Makoto
    Kuwahata, Taisaku
    Miyazaki, Yumi
    Tsukasa, Koichirou
    Hayashi, Tomomi
    Shinchi, Hiroyuki
    Natsugoe, Shoji
    Takao, Sonshin
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 17 (07)
  • [45] Hypoxia-Induced Snail Expression Through Transcriptional Regulation by HIF-1α in Pancreatic Cancer Cells
    Guang-hui Zhu
    Chen Huang
    Zheng-zhong Feng
    Xiu-hong Lv
    Zheng-jun Qiu
    Digestive Diseases and Sciences, 2013, 58 : 3503 - 3515
  • [46] Hypoxia-Induced Snail Expression Through Transcriptional Regulation by HIF-1α in Pancreatic Cancer Cells
    Zhu, Guang-hui
    Huang, Chen
    Feng, Zheng-zhong
    Lv, Xiu-hong
    Qiu, Zheng-jun
    DIGESTIVE DISEASES AND SCIENCES, 2013, 58 (12) : 3503 - 3515
  • [47] HIF-1 maintains a functional relationship between pancreatic cancer cells and stromal fibroblasts by upregulating Shh
    Kobayashi, Minoru
    Katagiri, Tomohiro
    Hiraoka, Masahiro
    Harada, Hiroshi
    CANCER SCIENCE, 2018, 109 : 1283 - 1283
  • [48] The role of HIF-1 protein on the radiosensitizing effect of difluorodeoxyuridine, the main metabolite of gemcitabine, under normoxic and anoxic conditions
    Pauweis, Bea
    Wouters, An
    Vermorken, Jan B.
    Ides, Johan
    Deschoolmeester, Vanessa
    Lambrechts, Hilde A. J.
    Pattyn, Greet G. O.
    Meijnders, Paul
    Pauwels, Patrick
    Williams, Kaye J.
    Peeters, Marc
    Lardon, Filip
    CANCER RESEARCH, 2011, 71
  • [49] Nitric oxide impairs normoxic degradation of HIF-1α by inhibition of prolyl hydroxylases
    Metzen, E
    Zhou, J
    Jelkmann, W
    Fandrey, J
    Brüne, B
    MOLECULAR BIOLOGY OF THE CELL, 2003, 14 (08) : 3470 - 3481
  • [50] Overexpression of MMP-9 and HIF-1α in breast cancer cells under hypoxic conditions
    Jaeyoung, C.
    Jeongyoon, S.
    Sunyoung, M.
    SuckHwan, K.
    HaiLin, P.
    BREAST, 2011, 20 : S17 - S18
12345