Detailed analysis of immunologic effects of the cytotoxic T lymphocyte-associated antigen 4-blocking monoclonal antibody tremelimumab in peripheral blood of patients with melanoma

被引:0
|
作者
Begoña Comin-Anduix
Yohan Lee
Jason Jalil
Alain Algazi
Pilar de la Rocha
Luis H Camacho
Viviana A Bozon
Cecile A Bulanhagui
Elisabeth Seja
Arturo Villanueva
Bradley R Straatsma
Antonio Gualberto
James S Economou
John A Glaspy
Jesus Gomez-Navarro
Antoni Ribas
机构
[1] University of California Los Angeles (UCLA),Department of Surgery, Division of Surgical Oncology
[2] UCLA,Department of Human Genetics
[3] Oncology Consultants PA,Department of Medicine, Division of Hematology/Oncology
[4] Pfizer Global Research and Development (PGRD),Department of Ophthalmology
[5] UCLA,Department of Microbiology
[6] Jules Stein Eye Institute,Jonsson Comprehensive Cancer Center
[7] UCLA,undefined
[8] Immunology and Molecular Genetics,undefined
[9] UCLA,undefined
来源
Journal of Translational Medicine | / 6卷
关键词
Melanoma; Peripheral Blood Mononuclear Cell; ELISPOT Assay; Immune Monitoring; FoxP3 mRNA;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: A phase I/II study
    Maker, AV
    Phan, GQ
    Attia, P
    Yang, JC
    Sherry, RM
    Topalian, SL
    Kammula, US
    Royal, RE
    Haworth, LR
    Levy, C
    Kleiner, D
    Mavroukakis, SA
    Yellin, M
    Rosenberg, SA
    ANNALS OF SURGICAL ONCOLOGY, 2005, 12 (12) : 1005 - 1016
  • [32] Cytotoxic T Lymphocyte-Associated Antigen 4 Gene Polymorphisms and Autoimmune Thyroid Diseases: An Updated Systematic Review and Cumulative Meta-Analysis
    Hou, Hai-Feng
    Jin, Xu
    Sun, Tao
    Li, Cheng
    Jiang, Bao-Fa
    Li, Qun-Wei
    INTERNATIONAL JOURNAL OF ENDOCRINOLOGY, 2015, 2015
  • [33] The Goat Cytotoxic T Lymphocyte-Associated Antigen-4 Gene: mRNA Expression and Association Analysis of Insertion/Deletion Variants with the Risk of Brucellosis
    Wang, Congliang
    Liu, Xiaoyu
    Ren, Zhaofei
    Du, Xiaomin
    Li, Na
    Song, Xiaoyue
    Wu, Weiwei
    Qu, Lei
    Zhu, Haijing
    Hua, Jinlian
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (20)
  • [34] MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4
    Sonkoly, Eniko
    Janson, Peter
    Majuri, Marja-Leena
    Savinko, Terhi
    Fyhrquist, Nanna
    Eidsmo, Liv
    Xu, Ning
    Meisgen, Florian
    Wei, Tianling
    Bradley, Maria
    Stenvang, Jan
    Kauppinen, Sakari
    Alenius, Harri
    Lauerma, Antti
    Homey, Bernhard
    Winqvist, Ola
    Stahle, Mona
    Pivarcsi, Andor
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2010, 126 (03) : 581 - U306
  • [35] EFFECTS OF CYTOTOXIC T LYMPHOCYTE-ASSOCIATED ANTIGEN 4 IMMUNOGLOBULIN COMBINED WITH MICROBUBBLE-MEDIATED IRRADIATION ON HEMODYNAMICS OF THE RENAL ARTERY IN RATS WITH DIABETIC NEPHROPATHY
    Wang, Liang
    Li, Xiuyun
    Dong, Yanyan
    Wang, Pengfei
    Xu, Maosheng
    Zheng, Chao
    Jiao, Yan
    Zou, Chunpeng
    ULTRASOUND IN MEDICINE AND BIOLOGY, 2020, 46 (03): : 703 - 711
  • [36] Ad5/3-delta24-aCTLA4, a targeted oncolytic adenovirus producing a human full-length monoclonal antibody for cytotoxic T lymphocyte-associated antigen 4 (CTLA-4)
    Dias, J.
    Hemminki, O.
    Ranki, T.
    Bonetti, A.
    Guse, K.
    Diaconu, I.
    Escutenaire, S.
    Kanerva, A.
    Pesonen, S.
    Cerullo, V.
    Hemminki, A.
    HUMAN GENE THERAPY, 2011, 22 (10) : A71 - A71
  • [37] Association of the cytotoxic T lymphocyte-associated antigen 4 gene with type 1 diabetes: Evidence for independent effects of two polymorphisms on the same haplotype block
    Anjos, SM
    Tessier, MC
    Polychronakos, C
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2004, 89 (12): : 6257 - 6265
  • [38] A dose escalation phase 1 study of radiotherapy (RT) in combination with anti-cytotoxic-T-lymphocyte-associated antigen 4 (CTLA-4) monoclonal antibody ipilimumab (Ipi) in patients (pts) with metastatic melanoma
    Boutros, C.
    Mateus, C.
    Routier, E.
    Chouaib, S.
    Libenciuc, C.
    Reigneau, M.
    Girault, I.
    Caramella, C.
    Hibat, S.
    Vagner, S.
    Tao, Y. G.
    Chaput, N.
    Adam, J.
    Soria, J-C.
    Eggermont, A.
    Deutsch, E.
    Robert, C.
    ANNALS OF ONCOLOGY, 2016, 27
  • [39] Tumor regression and autoimmunity in metastatic melanoma patients treated with cytotoxic T lymphocyte associated antigen 4 blockade and interleukin-2
    Maker, AV
    Phan, GQ
    Attia, P
    Rosenberg, SA
    ANNALS OF SURGICAL ONCOLOGY, 2005, 12 (02) : S18 - S18
  • [40] The role and relationship between programmed death ligand 1 and cytotoxic T lymphocyte-associated antigen-4 immunohistochemical expression in colorectal carcinoma patients: an impact on outcome
    Mohamed, Asmaa Shams El Dein
    El-Rebey, Hala Said
    AboElnasr, Lamia Sabry Abdelsamed
    Abdou, Asmaa Gaber
    ECANCERMEDICALSCIENCE, 2021, 15